NCT03140046

Visual Outcomes of Topography Guided Photorefractive Keratectomy (PRK) for Treatment of Patients With Irregular Cornea

Completed NA Last updated 11 May 2020

What this trial tests

NA trial testing photorefractive keratectomy (PRK) in Irregular Astigmatism in 20 participants. Completed in 1 March 2018.

Timeline

1 March 2017

Primary endpoint
1 March 2018

1 March 2018

Quick facts

Lead sponsor	Assiut University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	20
Start date	1 March 2017
Primary completion	1 March 2018
Estimated completion	1 March 2018
Sites	1 location across Egypt

Drugs / interventions tested

• photorefractive keratectomy (PRK)

Conditions studied

• Irregular Astigmatism — all drugs for Irregular Astigmatism →

Sponsor

Assiut University

Who can join

Eligibility, any sex, with Irregular Astigmatism. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Irregular astigmatism is one of the most serious and frequent complications of corneal refractive surgery and one of the worst sequelae of other forms of corneal surgery . It is also considered as one of common, serious complications of corneal injuries .

Spectacle correction is usually not useful in the correction of corneal irregular astigmatism. Contact lenses represent a good alternative, but their adaptation and stability are limited by the irregular corneal surface and patient discomfort.

In recent years, advancements in laser technology have offered better tools for dealing with irregular astigmatism with finding new surgical methods to improve corneal regularity for the correction of irregular astigmatism.

Topography-linked excimer laser is a potentially effective technique in the treatment of irregular astigmatism after keratoplasty . In fact, customized ablation was shown to be an effective means of treatment of irregular astigmatism due to different etiologies Such as corneal Injuries , scar , or postoperative.

Some of the theoretical advantages of topography-driven photorefractive keratectomy (PRK) are a better astigmatic correction, the possibility of correcting irregular astigmatism, and a smaller ablation volume compared with standard treatments, resulting in better visual performance.

Aim of the work To evaluate the efficacy, safety, and predictability of topography-guided photorefractive keratectomy (PRK) to improve refractive status of patient with irregular Cornea.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.