NCT03136549

Cuff Inflation-supplemented Videoscope-guided Nasal Intubation

Completed NA Last updated 29 January 2026

What this trial tests

NA trial testing Thermo-softening in Nasotracheal Intubation in 140 participants. Completed in 1 December 2017.

Timeline

10 June 2017

Primary endpoint
1 December 2017

1 December 2017

Quick facts

Lead sponsor	Hallym University Kangnam Sacred Heart Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	prevention
Enrollment	140
Start date	10 June 2017
Primary completion	1 December 2017
Estimated completion	1 December 2017
Sites	1 location across South Korea

Drugs / interventions tested

• Thermo-softening
• Room temperature

Conditions studied

• Nasotracheal Intubation — all drugs for Nasotracheal Intubation →

Sponsor

Hallym University Kangnam Sacred Heart Hospital

Who can join

18 and older, any sex, with Nasotracheal Intubation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Epistaxis or post-pharyngeal bleeding is the most common complication after nasotracheal intubation (NTI). Prior thermal softening of the endotracheal tube (ET) has been recommended as one of the methods to prevent nasal trauma from nasotracheal intubation. However, thermal softening of tubes tends to adversely affect the nasotracheal navigation of the ET.

During NTI under conventional direct laryngoscopy, the tip of the Macintosh laryngoscope is advanced into the vallecula, indirectly elevating the epiglottis by applying pressure on the hyoepiglottic ligament. Although this maneuver allows optimal visualization of the glottis, it lifts the larynx away from the tip of the advancing nasotracheal tube (NTT), which generally lies along the posterior pharyngeal wall. Most clinicians use Magill forceps to direct the tip of the NTT anteriorly to enter the glottis. Magill forceps may cause damage to the cuff of an ET or may injure oropharyngeal mucosa.

The use of a video laryngoscope and a cuff inflation technique has been proposed as a method for reducing the malalignment of tubes. Indirect laryngoscopy using a Video laryngoscopy can reduce malalignment by minimizing lifting the glottis during laryngoscopy. The cuff inflation technique (wherein the cuff of ET tube is inflated with 15 mL of air) has been used while performing "blind" NTI to guide such malaligned polyvinyl chloride (PVC) ET tubes into the laryngeal inlet. Recently, one study reported that the cuff inflation technique consistently improved the oropharyngeal insertion of the different ET tubes of varying stiffness during direct laryngoscope-guided NTI.

There has never been study about effect of cuff inflation technique on navigability when performing NTI under video laryngoscopy guidance with ET tubes of varying stiffness.Investigators assessed and compared the incidence of nasal injury and nasotracheal navigability with two technique during cuff inflation-supplemented NTI guided by video- laryngoscopy

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.