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NCT03134430
Effects of Regional Nerve Block on Cancer Recurrence
NA trial testing Normal saline in Cancer Patient in 400 participants. Status unknown.
25 March 2018
Quick facts
| Lead sponsor | Luo Foquan |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 400 |
| Start date | 10 July 2017 |
| Primary completion | 25 March 2018 |
| Estimated completion | 1 May 2023 |
| Sites | 1 location across China |
Drugs / interventions tested
- Normal saline
- peripheral Nerve block — full drug profile →
Conditions studied
- Cancer Patient — all drugs for Cancer Patient →
Sponsor
Luo Foquan
Who can join
Adults 18 to 80, any sex, with Cancer Patient. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
It has been reported local anesthetics could inhibit tumor cell proliferation, metastasis and invasion ability，but it is still lack of clinical evidence. Our study aims to explore the effects of regional nerve block on cancer recurrence and the mechanism.
Publications & conference data
5 peer-reviewed publications reference this trial (live from Europe PMC):
-
Sodium homeostasis in the tumour microenvironment.
Leslie TK, James AD, Zaccagna F, Grist JT, et al · · 2019 · cited 101× · PMID 31348974 · DOI 10.1016/j.bbcan.2019.07.001 -
Repositioning Lidocaine as an Anticancer Drug: The Role Beyond Anesthesia.
Zhou D, Wang L, Cui Q, Iftikhar R, et al · · 2020 · cited 35× · PMID 32766241 · DOI 10.3389/fcell.2020.00565 -
Local Anesthetics and Recurrence after Cancer Surgery-What's New? A Narrative Review.
Müller SD, Ziegler JSH, Piegeler T. · · 2021 · cited 19× · PMID 33670434 · DOI 10.3390/jcm10040719 -
Trial watch: local anesthetics in cancer therapy.
Carnet Le Provost K, Kepp O, Kroemer G, Bezu L. · · 2024 · cited 5× · PMID 38504848 · DOI 10.1080/2162402x.2024.2308940 -
Anaesthetic Techniques and Strategies: Do They Influence Oncological Outcomes?
Murphy L, Shaker J, Buggy DJ. · · 2023 · cited 3× · PMID 37366886 · DOI 10.3390/curroncol30060403
Verify or expand the search:
- PubMed search for NCT03134430
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03134430 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Luo Foquan
- Last refreshed: 25 May 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03134430.
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