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NCT03133299
A Study Evaluating Vitamin D in Allergic Bronchopulmonary Aspergillosis Complicating Asthma
Phase 2, PHASE3 trial testing Glucocorticoids in Allergic Bronchopulmonary Aspergilloses in 30 participants. Completed in 30 June 2018.
30 June 2018
Quick facts
| Lead sponsor | Post Graduate Institute of Medical Education and Research, Chandigarh |
|---|---|
| Phase | Phase 2, PHASE3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 1 December 2016 |
| Primary completion | 30 June 2018 |
| Estimated completion | 30 June 2018 |
| Sites | 1 location across India |
Drugs / interventions tested
- Glucocorticoids — full drug profile →
- Vitamin D
Conditions studied
- Allergic Bronchopulmonary Aspergilloses — all drugs for Allergic Bronchopulmonary Aspergilloses →
Sponsor
Post Graduate Institute of Medical Education and Research, Chandigarh
Who can join
Adults 18 to 65, any sex, with Allergic Bronchopulmonary Aspergilloses. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Allergic bronchopulmonary aspergillosis (ABPA) is a immunological pulmonary disorder caused by hypersensitive reaction to spores of Aspergillus fumigatus. The prevalence of disease is about 1-2% in asthmatics and 2-15% in patients with cystic fibrosis. The interest in ABPA stems from the fact that the disease is glucocorticoid-sensitive and early treatment can prevent progression to end-stage lung disease. Recently anti-Th2 therapies have been suggested as treatment for ABPA. Vitamin D has been shown to suppress the Th2 responses and decrease the levels of Th2 interleukins. Hence, the investigators propose to assess the role of vitamin D in treating ABPA.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A randomised trial of vitamin D in acute-stage allergic bronchopulmonary aspergillosis complicating asthma.
Dodamani MH, Muthu V, Thakur R, Pal A, et al · · 2019 · cited 22× · PMID 30561849 · DOI 10.1111/myc.12879
Verify or expand the search:
- PubMed search for NCT03133299
- Europe PMC full search
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03133299 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Post Graduate Institute of Medical Education and Research, Chandigarh
- Last refreshed: 23 August 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03133299.
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