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NCT03130374
Treatment of Laryngotracheal Stenosis Using Mesenchymal Stem Cells
Phase 1, PHASE2 trial testing Olfactory mucosa-derived mesenchymal stem cells in Tracheal Stenosis in 12 participants. Completed in 20 May 2019.
4 January 2019
Quick facts
| Lead sponsor | The Republican Research and Practical Center for Epidemiology and Microbiology |
|---|---|
| Phase | Phase 1, PHASE2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 12 |
| Start date | 3 January 2017 |
| Primary completion | 4 January 2019 |
| Estimated completion | 20 May 2019 |
| Sites | 2 locations across Belarus |
Drugs / interventions tested
- Olfactory mucosa-derived mesenchymal stem cells — full drug profile →
Conditions studied
- Tracheal Stenosis — all drugs for Tracheal Stenosis →
- Laryngeal Stenosis — all drugs for Laryngeal Stenosis →
- Mesenchymal Stem Cells — all drugs for Mesenchymal Stem Cells →
Sponsor
The Republican Research and Practical Center for Epidemiology and Microbiology — full company profile →
Who can join
Adults 18 to 85, any sex, with Tracheal Stenosis or Laryngeal Stenosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The trial evaluates the safety and efficacy of the olfactory mucosa-derived mesenchymal stem cells based therapy for the patients with chronic laryngeal and tracheal stenosis
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
The Clinical Trials of Mesenchymal Stromal Cells Therapy.
Kouchakian MR, Baghban N, Moniri SF, Baghban M, et al · · 2021 · cited 30× · PMID 34745268 · DOI 10.1155/2021/1634782 -
Abstracts TPS
· 2019 · cited 4×
Verify or expand the search:
- PubMed search for NCT03130374
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Olfactory mucosa-derived mesenchymal stem cells
Trials testing the same drug.
- NCT05167552 — Treatment of Allergic Rhinitis and Chronic Polypous Rhinosinusitis With Olfactory Mucosa-derived Mesenchymal Stem Cells · Phase 1, PHASE2 · unknown
- NCT05535803 — Treatment of Laryngotracheal Stenosis Using Mesenchymal Stem Cells · Phase 2 · unknown
Other recruiting trials for Tracheal Stenosis
Currently open trials in the same condition.
- NCT07258784 — RNA Sequencing of Discarded Tracheal Stenosis Tissue to Characterize Cellular and Molecular Pathogenesis · recruiting
- NCT06917222 — Slide Tracheoplasty Versus Tracheal Resection Anastomosis in Acquired Tracheal Stenosis · NA · recruiting
Other The Republican Research and Practical Center for Epidemiology and Microbiology trials
Trials by the same sponsor.
- NCT05908162 — Algorithm for Predicting the Unfavorable Course of Sepsis in Children · completed
- NCT04392297 — Clinical and Immunological Features of the CMV Infection Atypical Course in Immunocompetent Individuals · completed
- NCT04178915 — Study of Leukocyte Immunophenotype and the Lipid Transport System as Predictive Biomarkers of Severe Bacterial Infection · enrolling by invitation
- NCT03114631 — Dendritic Cell Immunotherapy for the Patients With Pancreatic Cancer · Phase 1, PHASE2 · completed
- NCT03161951 — Differential Diagnostics of Etiology of Acute Infections · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03130374 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Republican Research and Practical Center for Epidemiology and Microbiology
- Last refreshed: 7 June 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03130374.
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