Hemodynamics and Vital Organ Function in Intracerebral Hemorrhage

NCT03129009 NA UNKNOWN

Spontaneous non-traumatic intracerebral hemorrhage (ICH) is a common symptom in clinical practice and is the most serious among all types of stroke.Recently, as a relatively mainstream and recognized INTERACT2 (five well-known international studies in the cerebrovascular field: IMS-III, MR RESCUE, SYNTHESIS EXPANSION, INTERACT2, CHANCE) studies have shown that in patients with standard systolic blood pressure Early intensive antihypertensive therapy does not increase the incidence of death or serious adverse events. The above studies confirm the safety and efficacy of early potent depression.In 2017, Anesthesiology published a META analysis of intraoperative hypotension and blood pressure versus baseline fluctuations. The final outcome showed that 20% of blood pressure in the study was similar to MAP \<65 mmHg, regardless of the duration of the duration There will be postoperative myocardial and renal damage. Ischemia is a very important cause of organ damage. Myocardial injury is closely related to the level of mean arterial pressure, while ischemia and ischemic reperfusion injury are closely related to postoperative acute renal injury.There is no targeted guideline for ICH perioperative blood pressure management, especially intraoperative blood pressure management, and no previous studies have studied most of the studies involving ICH patients with conservative treatment, ICH patients with surgical treatment There are few reports on blood pressure control during surgery.

Details

Lead sponsor	Xuzhou Medical University
Phase	NA
Status	UNKNOWN
Enrolment	90
Start date	Sat Apr 01 2017 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Fri Jun 01 2018 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Balanced Anesthesia
• Intracerebral Hemorrhage
• Total Intravenous Anesthesia

Interventions

• Total intravenous anesthesia group
• Balanced anesthesia group

Countries

China