NCT03121911 is a NA clinical trial of Interval Training (IT) in Expiratory Flow Limitation, sponsored by Federal University of Uberlandia.

Who is sponsoring NCT03121911?

NCT03121911 is sponsored by Federal University of Uberlandia.

What drugs are being tested in NCT03121911?

Interventions in NCT03121911: Interval Training (IT), Inspiratory Muscle Training (IMT).

What condition does NCT03121911 study?

NCT03121911 studies Expiratory Flow Limitation, Recent Myocardial Infarction.

Is NCT03121911 still recruiting?

NCT03121911 is currently withdrawn. Last updated 5 May 2020.

Last reviewed 2020-05-05 · How we verify

NCT03121911

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Interval Physical Training on Expiratory Flow Limitation in Recent Myocardial Infarction

Withdrawn NA Last updated 5 May 2020

What this trial tests

NA trial testing Interval Training (IT) in Expiratory Flow Limitation. Withdrawn.

Timeline

4 July 2019

Primary endpoint
28 February 2021

31 October 2022

Quick facts

Lead sponsor	Federal University of Uberlandia
Phase	NA
Status	Withdrawn
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Start date	4 July 2019
Primary completion	28 February 2021
Estimated completion	31 October 2022
Sites	1 location across Brazil

Drugs / interventions tested

Interval Training (IT)
Inspiratory Muscle Training (IMT)

Conditions studied

Expiratory Flow Limitation — all drugs for Expiratory Flow Limitation →
Recent Myocardial Infarction — all drugs for Recent Myocardial Infarction →

Sponsor

Federal University of Uberlandia

Who can join

Adults 35 to 80, male only, with Expiratory Flow Limitation or Recent Myocardial Infarction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Introduction: Expiratory flow limitation (EFL) and ventilatory inefficiency during dynamic exercise have been identified in patients with recent myocardial infarction (RMI) with preserved ventricular and pulmonary function. However, it is not known what is the prevalence of EFL in this population and what are the effects of physical and respiratory training on this limitation. Objectives: To evaluate the prevalence of EFL and ventilatory inefficiency during dynamic exercise in individuals with uncomplicated RMI, and to evaluate the effects of interval physical training (IT) in addition to inspiratory muscle training (IMT), exclusive IT and absence of cardiopulmonary rehabilitation (CR) on EFL and ventilatory efficiency. Methods: 54 patients will be included, divided into three groups with 18 participants each. All will be submitted to evaluations of heart rate variability, hematological and biochemical profile, erythrocytes membrane deformability and stability, inflammatory markers, respiratory pressures, plethysmography, spirometry, carbon monoxide diffusion capacity, ankle brachial index, electrical bioimpedance, echocardiogram, quality of life questionnaires, cardiopulmonary exercise testing and constant load tests. Then, groups 1 (IT) and group 2 (IT + IMT) will participate in a physical training program for 12 weeks and will be re-evaluated after this period. In addition, they will be monitored for a 6 month period after discharge, with returns every two months to measure the energy expenditure through an accelerometer, and at the end of this period they will repeat all the tests again. Group 3 (absence of CR), will consist of patients who do not live in the city or those who can not participate in the CR program for any other reason, and will only participate in the evaluations.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03121911 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Federal University of Uberlandia
Last refreshed: 5 May 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03121911.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing