Last reviewed · How we verify
NCT03117946: i-RTCT
Modulation of Anti-tumor T Cell Responses in Cancer Patients Treated by Concomitant Radiochemotherapy
NA trial testing Biological samples in Lung Cancer in 220 participants. Currently enrolling.
29 August 2026
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire de Besancon |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 220 |
| Start date | 29 May 2017 |
| Primary completion | 29 August 2026 |
| Estimated completion | 29 November 2026 |
| Sites | 4 locations across France |
Drugs / interventions tested
- Biological samples — full drug profile →
Conditions studied
- Lung Cancer — all drugs for Lung Cancer →
- Head and Neck Cancer — all drugs for Head and Neck Cancer →
Sponsor
Centre Hospitalier Universitaire de Besancon
Who can join
18 and older, any sex, with Lung Cancer or Head and Neck Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to evaluate modulation of anti-tumor T cell responses in cancer patients treated by concomitant radiochemotherapy (i-RTCT)
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Neural influences in colorectal cancer progression and therapeutic strategies.
Zeng Z, Cai S, Ye C, Li T, et al · · 2025 · cited 6× · PMID 40379990 · DOI 10.1007/s00384-025-04887-w -
Multidimensional immune profiling uncovers biphasic peripheral T-cell dynamics after chemoradiation in patients with locally advanced head and neck cancer.
Lecoester B, Xie Y, Sun X, Renaudin A, et al · · 2026 · PMID 41749511 · DOI 10.1080/2162402x.2026.2635806
Verify or expand the search:
- PubMed search for NCT03117946
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Biological samples
Trials testing the same drug.
- NCT07119086 — Factors Associated With Hospitalization and Severity of Arbovirosis in the Indian Ocean · NA · recruiting
- NCT06415422 — Platelet Activity Monitoring for Patients Under Adp Medication Using Verify Now in Subdural Hematoma · NA · not yet recruiting
- NCT06444503 — Clinico-biological Collection of Bone, Calcium and Growth Plate Pathologies · recruiting
- NCT06334406 — Antitumor T Cell Responses in Patients With Bladder Cancer · unknown
- NCT06242509 — Intestinal Akkermansia Muciniphila in Prostate Cancer · unknown
Other recruiting trials for Lung Cancer
Currently open trials in the same condition.
- NCT07295821 — Osimertinib Induction and Maintenance for Chemo-ineligible Stage III Unresectable EGFR+ NSCLC: Single-arm Study · Phase 2 · recruiting
- NCT06909201 — Hyperpolarized Xenon-129 Magnetic Resonance Imaging in Lung Cancer Patients Receiving Radiation Therapy for Investigatin · Phase 1 · recruiting
- NCT07524114 — Study of High-Precision Evaluation of Molecular ResiduaL Disease Through a PlatfOrm for Cancer TracKing and Interception · recruiting
- NCT07487064 — Galvanize Aliya® EX Pulsed Electric Field (PEF) Treat and Resect Study · NA · recruiting
- NCT07146568 — Evaluating the Implementation and Effectiveness of the Pink and Pearl Campaign on Lung Cancer Screening at Christian Hos · NA · recruiting
Other Centre Hospitalier Universitaire de Besancon trials
Trials by the same sponsor.
- NCT07492199 — High Depth Exome Sequencing on DNA From a Salivary Sample by Mouth Smear. · not yet recruiting
- NCT07438015 — VEXUS-REA : Evaluation of Ultrasound Parameters of Venous Congestion in Patients in a Medical Intensive Care Unit · NA · not yet recruiting
- NCT06796114 — Identification of Innovative Biomarkers to Predict Outcomes in Hepatocellular Carcinoma Treated With Tremelimumab and Du · NA · recruiting
- NCT06864065 — Study of Emotional Regulation and Underlying Prefrontal Activity in Binge Eating Disorder · NA · recruiting
- NCT07067762 — Botulinum Toxin Injections Into the Salivary Glands of Cerebrospinal Children With Chronic Sialorrhea · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03117946 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire de Besancon
- Last refreshed: 27 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03117946.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing