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NCT03117231
Effects of tDCS in Elderly With Pain Due to Knee Osteoarthritis
NA trial testing Active Transcranial Direct Current Stimulation (tDCS) in Osteoarthritis, Knee in 104 participants. Completed in 1 July 2019.
1 June 2019
Quick facts
| Lead sponsor | Federal University of São Paulo |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 104 |
| Start date | 15 March 2018 |
| Primary completion | 1 June 2019 |
| Estimated completion | 1 July 2019 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Active Transcranial Direct Current Stimulation (tDCS)
- Sham Transcranial Direct Current Stimulation (tDCS)
Conditions studied
- Osteoarthritis, Knee — all drugs for Osteoarthritis, Knee →
- Chronic Pain — all drugs for Chronic Pain →
Sponsor
Federal University of São Paulo
Who can join
60 and older, any sex, with Osteoarthritis, Knee or Chronic Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to evaluate if anodal tDCS stimulation over M1 may decrease chronic knee OA pain in elderly subjects with defective CPM. In addition, this trial will help to investigate the role of central sensitization in knee OA and evaluate how tDCS stimulation may affect it.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Risk factors of pain, physical function, and health-related quality of life in elderly people with knee osteoarthritis: A cross-sectional study.
Tavares DRB, Moça Trevisani VF, Frazao Okazaki JE, Valéria de Andrade Santana M, et al · · 2020 · cited 19× · PMID 33376818 · DOI 10.1016/j.heliyon.2020.e05723 -
Effects of Transcranial Direct Current Stimulation on Knee Osteoarthritis Pain in Elderly Subjects With Defective Endogenous Pain-Inhibitory Systems: Protocol for a Randomized Controlled Trial.
Tavares DRB, Okazaki JEF, Rocha AP, Santana MVA, et al · · 2018 · cited 17× · PMID 30373731 · DOI 10.2196/11660 -
Development of a Clinical Prediction Rule for Treatment Success with Transcranial Direct Current Stimulation for Knee Osteoarthritis Pain: A Secondary Analysis of a Double-Blind Randomized Controlled Trial.
Teixeira PEP, Tavares DRB, Pacheco-Barrios K, Branco LC, et al · · 2022 · cited 2× · PMID 36672512 · DOI 10.3390/biomedicines11010004
Verify or expand the search:
- PubMed search for NCT03117231
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Other recruiting trials for Osteoarthritis, Knee
Currently open trials in the same condition.
- NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
- NCT06488144 — Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans · Phase 3 · recruiting
- NCT07386561 — Virtual Reality Therapy and Non-Sleep Deep Rest Relaxation After Joint Arthroplasty · NA · active not recruiting
- NCT07514598 — Effect of J-Shaped Incision After Total Knee Arthroplasty (J-TKA) · NA · active not recruiting
- NCT07058623 — Nurse-Led Telehealth vs In-Person Follow-Up After Total Knee Replacement · NA · recruiting
Other Federal University of São Paulo trials
Trials by the same sponsor.
- NCT07376811 — Effect Of Sleeping Posture Guidance On Sleep Quality In Patients With Rotator Cuff Syndrome · NA · not yet recruiting
- NCT06805656 — Multi Interventional Approaches to Mitigate HIV Reservoirs Aiming the Sustained HIV Remission Without Antiretrovirals · Phase 2 · not yet recruiting
- NCT06970964 — Fermented Milk Drink With Lacticaseibacillus Paracasei Strain Shirota Helps Triathletes With Cold-Like Symptoms Before a · NA · completed
- NCT06905860 — Intra-articular Infiltration of Platelet-Rich Fibrin vs Corticosteroid in Mild to Moderate Knee Osteoarthritis · Phase 4 · not yet recruiting
- NCT06829992 — Effects of Applying Kinesio Tapping on Primary Dysmenorrhea in Football Players · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03117231 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Federal University of São Paulo
- Last refreshed: 9 September 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03117231.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing