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NCT03112499
The Effect of Three Endourological Procedures for the Management of Renal Calculi Regarding Acute Kidney Injury
NA trial testing PCNL in Renal Calculi in 75 participants. Completed in 15 June 2021.
15 March 2021
Quick facts
| Lead sponsor | Institute for the Study of Urological Diseases, Greece |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | other |
| Enrollment | 75 |
| Start date | 5 June 2018 |
| Primary completion | 15 March 2021 |
| Estimated completion | 15 June 2021 |
| Sites | 1 location across Greece |
Drugs / interventions tested
- PCNL
- mini-PCNL
- RIRS
Conditions studied
- Renal Calculi — all drugs for Renal Calculi →
- Renal Insufficiency — all drugs for Renal Insufficiency →
Sponsor
Institute for the Study of Urological Diseases, Greece
Who can join
18 and older, any sex, with Renal Calculi or Renal Insufficiency. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The main aim of the study is to investigate and compare the possible acute effect of standard PCNL, mini-PCNL and RIRS on renal function. Secondary aims are to investigate the efficacy (stone-free rate), safety (complication rate, long-term kidney function) and other parameters (operation, fluoroscopy and hospitalization time) concerning the 3 endourological operations (PCNL, mini- PCNL, RIRS) for the treatment of renal calculi.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Percutaneous nephrolithotomy versus retrograde intrarenal surgery for treatment of renal stones in adults.
Soderberg L, Ergun O, Ding M, Parker R, et al · · 2023 · cited 19× · PMID 37955353 · DOI 10.1002/14651858.cd013445.pub2 -
Are endourological procedures for nephrolithiasis treatment associated with renal injury? A review of potential mechanisms and novel diagnostic indexes.
Mykoniatis I, Sarafidis P, Memmos D, Anastasiadis A, et al · · 2020 · cited 7× · PMID 32905259 · DOI 10.1093/ckj/sfaa020 -
The effect of standard percutaneous nephrolithotomy, miniaturized percutaneous nephrolithotomy and retrograde intrarenal surgery on biomarkers of renal injury: a randomized clinical trial.
Memmos D, Sarafidis P, Alexandrou ME, Theodorakopoulou M, et al · · 2023 · cited 6× · PMID 37915926 · DOI 10.1093/ckj/sfad120
Verify or expand the search:
- PubMed search for NCT03112499
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of PCNL
Trials testing the same drug.
- NCT06914986 — A Prospective Multicenter Randomized Controlled Trial of Flexible And Navigable Suction Ureteral Access Sheath Combined · NA · not yet recruiting
- NCT06350045 — High Supracostal Versus Subcostal Puncture in Adult PCNL · Phase 4 · active not recruiting
- NCT07355907 — Preoperative Prophylactic Fosfomycin Trometamol Versus 5-day Levofloxacin in Prevention of Postpercutaneous Nephrolithot · NA · completed
- NCT04069013 — Standard vs Mini-PCNL for the Treatment of Stone Disease · NA · completed
- NCT05291702 — Multitract Percutaneous Nephrolithotomy(PCNL) in Large Renal Stones. · NA · unknown
Other recruiting trials for Renal Calculi
Currently open trials in the same condition.
- NCT07360353 — Comparison Between Different Types of Flexible Ureteroscopes · NA · recruiting
- NCT07342361 — Using Retrograde Intrarenal Surgery for Managing Staghorn Renal Stones. · NA · recruiting
- NCT07261995 — Comparison of Extracorporeal Shock Wave Lithotripsy Versus Retrograde Intrarenal Surgery in the Management of Renal Calc · NA · recruiting
- NCT06767384 — Diagnostic Accuracy of x Ray Kub in Diagnosing Renal Calculi Keeping CT Scan as Gold Standard · active not recruiting
- NCT03811171 — Break Wave(TM) Extracorporeal Lithotripter First-in-Human Study · NA · recruiting
Other Institute for the Study of Urological Diseases, Greece trials
Trials by the same sponsor.
- NCT04549389 — The Ideal LiST Session Frequency Protocol for CPPS Treatment · NA · completed
- NCT04050020 — Platelet-rich Plasma (PRP) Injection for Treatment of Erectile Function · Phase 2, PHASE3 · completed
- NCT03641846 — Low-intensity Shockwave Therapy (LiST) for the Treatment of Mild and Mild-to-moderate Vasculogenic Erectile Dysfunction · NA · completed
- NCT03543761 — Low-intensity Shockwave Therapy for Non-bacterial Prostatitis/Pelvic Pain Syndrome · NA · completed
- NCT03518983 — Low-intensity Shockwaves Therapy for the Treatment of Patients With Moderate Vasculogenic Erectile Dysfunction · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03112499 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Institute for the Study of Urological Diseases, Greece
- Last refreshed: 5 May 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03112499.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing