NCT03105115 is a NA clinical trial of fentanyl in Anesthesia, Spinal, sponsored by Seoul National University Hospital.

Who is sponsoring NCT03105115?

NCT03105115 is sponsored by Seoul National University Hospital.

What drugs are being tested in NCT03105115?

Interventions in NCT03105115: fentanyl, bupivacaine only.

What condition does NCT03105115 study?

NCT03105115 studies Anesthesia, Spinal.

Is NCT03105115 still recruiting?

NCT03105115 is currently completed. Last updated 29 August 2018.

Last reviewed 2018-08-29 · How we verify

NCT03105115

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Intrathecal Fentanyl on Spinal Anesthesia During Dexmedetomidine Infusion

Completed NA Last updated 29 August 2018

What this trial tests

NA trial testing fentanyl in Anesthesia, Spinal in 56 participants. Completed in 26 October 2017.

Timeline

25 May 2017

Primary endpoint
24 October 2017

26 October 2017

Quick facts

Lead sponsor	Seoul National University Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	56
Start date	25 May 2017
Primary completion	24 October 2017
Estimated completion	26 October 2017
Sites	1 location across South Korea

Drugs / interventions tested

fentanyl (fentanyl) — full drug profile →
bupivacaine only

Conditions studied

Anesthesia, Spinal — all drugs for Anesthesia, Spinal →

Sponsor

Seoul National University Hospital

Who can join

Adults 18 to 75, any sex, with Anesthesia, Spinal. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Intravenous infusion of dexmedetomidine during procedure was known to be associated prolonged duration of spinal anesthesia. In patients receiving dexmedetomidine infusion during procedure, it has been not evaluated whether use of adjuvant intrathecal fentanyl had additional prolonging effect on duration of spinal anesthesia or not. Therefore, the investigators planned this trial to compare clinical outcomes in patients receiving spinal anesthesia with heavy bupivacaine only and heavy bupivacaine plus fentanyl adjuvant.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Comparison of bupivacaine plus intrathecal fentanyl and bupivacaine alone for spinal anesthesia with intravenous dexmedetomidine sedation: a randomized, double-blind, noninferiority trial.
Park SK, Lee JH, Yoo S, Kim WH, et al · · 2019 · cited 4× · PMID 30679336 · DOI 10.1136/rapm-2018-100084

Verify or expand the search:

Other trials of fentanyl

Trials testing the same drug.

NCT07166666 — Study Comparing Atomizerd Midazolam & Fentanyl and Dexmedomidine for Procedural Sedation in Adult and Pediatric Patient · NA · not yet recruiting
NCT07078201 — Comparative Analysis of Intraoperative Effect Dexmedetomidine and Fentanyl as an Adjuvant to Heavy Bupivacaine in Spinal · Phase 4 · recruiting
NCT06868589 — Reducing Pain With Methadone and Ketamine in Liver Transplant · Phase 4 · active not recruiting
NCT07035223 — Clinical Comparative Study Aiming to Evaluate Postoperative Effect of Using Intrathecal Dexmedetomidine and Fentanyl as · Phase 4 · completed
NCT06799442 — Dexmedetomidine Versus Fentanyl as Adjuvants to Erector Spinae Plane Block for Postoperative Analgesia Following Simple · Phase 2, PHASE3 · not yet recruiting

Other recruiting trials for Anesthesia, Spinal

Currently open trials in the same condition.

NCT07050277 — Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine · Phase 3 · recruiting
NCT06878014 — Comparing the Safety and Effectiveness of Different Doses of Morphine Administered in Spinal Anethesia for Pain Relief A · Phase 4 · recruiting
NCT05824338 — Testing the Feasibility of Using Ropivacaine in Spinal Anesthesia for Patients With Lower Back Surgery · EARLY_PHASE1 · recruiting
NCT06434870 — Effect of Spinal Anesthesia in Elective Cesarean Cases on Frontal QRS Angle in Anemic and Non-Anemic Patients · recruiting
NCT06343259 — The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury · NA · recruiting

Other Seoul National University Hospital trials

Trials by the same sponsor.

NCT07262944 — EOI Block in Otoplasty With Rib Cartilage Graft · NA · recruiting
NCT07464210 — Nemtabrutinib, Bortezomib, and Rituximab for WM · Phase 2 · not yet recruiting
NCT07550803 — Effect of Intraoperative Dexamethasone on Early Postoperative Sleep Quality in Patients Undergoing Nasal Surgery · NA · not yet recruiting
NCT07522138 — Home-based Self-exercise in Patients With Parkinson's Disease: A Feasibility Study · NA · not yet recruiting
NCT07476651 — Scout Dose of Resin Microspheres · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03105115 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Seoul National University Hospital
Last refreshed: 29 August 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03105115.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing