NCT03096873

Combined Resistance and Aerobic Exercise Training on Obesity in Adolescent Girls

Completed NA Results posted Last updated 3 November 2020

What this trial tests

NA trial testing Combined Exercise Training in Obesity in 40 participants. Completed in 5 June 2011.

Timeline

3 March 2011

Primary endpoint
3 June 2011

5 June 2011

Quick facts

Lead sponsor	Pusan National University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	health services research
Enrollment	40
Start date	3 March 2011
Primary completion	3 June 2011
Estimated completion	5 June 2011

Drugs / interventions tested

• Combined Exercise Training

Conditions studied

• Obesity — all drugs for Obesity →

Sponsor

Pusan National University

Who can join

Adults 14 to 16, female only, with Obesity. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Height in Meters Primary · 12 weeks

Height was measured before and after 12 weeks.

Group	Value	95% CI
No Exercise (CON)	1.58	± 0.15
Exercise (EX)	1.60	± 0.11

Weight in Kilograms Primary · 12 weeks

Weight was measured before and after 12 weeks.

Group	Value	95% CI
No Exercise (CON)	75.8	± 1.5
Exercise (EX)	70.2	± 2.9

BMI in Weight (Kilograms)/Height (Meters)^2 Primary · 12 weeks

BMI was calculated with weight and height before and after 12 weeks.

Group	Value	95% CI
No Exercise (CON)	30	± 1.4
Exercise (EX)	27	± 2.1

Body Fat in Percents Primary · 12 weeks

Body fat was measured before and after 12 weeks.

Group	Value	95% CI
No Exercise (CON)	43	± 2.2
Exercise (EX)	39.6	± 2.1

Lean Body Mass in Percents Primary · 12 weeks

Lean body mass was measured before and after 12 weeks.

Group	Value	95% CI
No Exercise (CON)	43	± 2.2
Exercise (EX)	39.6	± 2.1

Waist Circumference in Centimeters Primary · 12 weeks

Waist circumference was measured before and after 12 weeks.

Group	Value	95% CI
No Exercise (CON)	88.2	± 1.0
Exercise (EX)	83.5	± 0.5

Glucose Levels in Millimole Per Liter Primary · 12 weeks

Glucose levels were measured before and after 12 weeks.

Group	Value	95% CI
No Exercise (CON)	5.4	± 0.1
Exercise (EX)	4.3	± 0.2

Insulin Levels in Micro Unit Per Milliliter Primary · 12 weeks

Insulin levels were measured before and after 12 weeks.

Group	Value	95% CI
No Exercise (CON)	27	± 2.4
Exercise (EX)	10.3	± 2.1

Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) Primary · 12 weeks

Homeostasis model assessment of Insulin Resistance (HOMA-IR) was calculated before and after 12 weeks

Group	Value	95% CI
No Exercise (CON)	6.5	± 0.6
Exercise (EX)	1.9	± 0.7

Leptin Levels in Nano Grams Per Milliliter Primary · 12 weeks

Leptin levels were measured before and after 12 weeks.

Group	Value	95% CI
No Exercise (CON)	22.5	± 2.3
Exercise (EX)	12.8	± 1.4

Adiponectin Levels in Micro Grams Per Milliliter Primary · 12 weeks

Adiponectin levels were measured before and after the training.

Group	Value	95% CI
No Exercise (CON)	5.7	± 0.5
Exercise (EX)	8.5	± 0.1

Volume of Maximal Oxygen Consumption (VO2max) Secondary · 12 weeks

Volume of maximal oxygen consumption (VO2max) was determined using a maximal treadmill test before and after 12 weeks.

Group	Value	95% CI
No Exercise (CON)	26	± 2.1
Exercise (EX)	27	± 1.2

Sponsor's own description

The purpose of the study was to observe therapeutic effects of combined resistance and aerobic exercise training (CRAE) on hyperinsulemia in obese adolescent girls. Forty obese adolescent girls (14±1 years) participated in this study. The participants were randomly separated into two groups; no-exercise group (n=20) and exercise group (n=20). The exercise group performed 12 weeks of CRAE.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.