Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative Hyperalgesia

NCT03096730 NA COMPLETED Results posted

To explore and compare antihyperalgesic effects of Dexmedetomidine,Nalmefene,and a combination of both received before anesthesia induction. To evaluate and examine the incidence of adverse effects with the purpose of selecting the optimum dose.

Details

Lead sponsor	Tianjin Medical University General Hospital
Phase	NA
Status	COMPLETED
Enrolment	150
Start date	Mon Feb 06 2017 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Sat Dec 30 2017 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Pain
• Anesthesia

Interventions

• Normal saline
• Remifentanil
• Sufentanil
• Dexmedetomidine injection
• Nalmefene

Countries

China