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NCT03093857: TAAA
Investigation of the Cerebrospinal Fluid and Further Tissue Samples for Biomarker Indicating Spinal Ischemia and Organ Failure in Patients With Thoracoabdominal Aortic Aneurysm
trial testing Determination of biomarker in Thoracoabdominal Aortic Aneurysm in 100 participants. Status unknown.
31 December 2018
Quick facts
| Lead sponsor | RWTH Aachen University |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 1 June 2014 |
| Primary completion | 31 December 2018 |
| Estimated completion | 31 December 2018 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Determination of biomarker
Conditions studied
- Thoracoabdominal Aortic Aneurysm — all drugs for Thoracoabdominal Aortic Aneurysm →
Sponsor
RWTH Aachen University
Who can join
18 and older, any sex, with Thoracoabdominal Aortic Aneurysm. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patients with a thoracoabdominal aortic aneurysm in need of an endovascular or open operative restructuring will be asked to participate in this study. After obtaining written consent a central venous catheter and a liquor drainage will be routinely placed during surgery. The catheter and the drainage will stay in the patients for at least 72 hours postoperatively. In total, nine measurements of the liquor and serum will be performed within a week in order to determine the following parameters: neuropeptide P, neuropeptide Y, neurofilament triplet protein (NFL), S100B, glial fibrillary protein (GFAp), lactate, glucose, or oxygen.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Hybrid repair versus conventional open repair for thoracic aortic arch aneurysms.
Elhelali A, Hynes N, Devane D, Sultan S, et al · · 2021 · cited 13× · PMID 34085713 · DOI 10.1002/14651858.cd012923.pub2 -
The Role of Ribonuclease 1 and Ribonuclease Inhibitor 1 in Acute Kidney Injury after Open and Endovascular Thoracoabdominal Aortic Aneurysm Repair.
Zechendorf E, Gombert A, Bülow T, Frank N, et al · · 2020 · cited 6× · PMID 33066382 · DOI 10.3390/jcm9103292 -
Macrophage Migration Inhibitory Factor Predicts Outcome in Complex Aortic Surgery.
Gombert A, Stoppe C, Foldenauer AC, Schuerholz T, et al · · 2017 · cited 3× · PMID 29120365 · DOI 10.3390/ijms18112374
Verify or expand the search:
- PubMed search for NCT03093857
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Thoracoabdominal Aortic Aneurysm
Currently open trials in the same condition.
- NCT07147569 — TAMBE Japan Post-Marketing Surveillance · recruiting
- NCT06478576 — Study on Multibranched Stent Graft System in the Treatment of Thoracoabdominal Aortic Aneurysm · NA · recruiting
- NCT05758844 — The Safe-line Technique as Additional Attempt to Mitigate Spinal Cord Ischemia After Endovascular Exclusion of TAAA · recruiting
- NCT06969729 — Evaluation of Clinical Efficacy and Safety of Aortal Stent-Graft Created Using 3D Printing Technology · NA · recruiting
- NCT07141251 — Clinical Trial of BAO-G Technique in Complex Aortic Aneurysm Endovascular Repair (BAO-G-02) · Phase 1 · recruiting
Other RWTH Aachen University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03093857 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by RWTH Aachen University
- Last refreshed: 29 March 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03093857.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing