Last reviewed · How we verify
NCT03093311
Near Infrared Spectroscopy for Detection of Cerebral Desaturation After Positioning for Neurosurgical Procedures
NA trial testing NIRS based protocol in Cognitive Dysfunction in 100 participants. Completed in 30 June 2019.
31 December 2018
Quick facts
| Lead sponsor | University Hospital Hradec Kralove |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 1 April 2017 |
| Primary completion | 31 December 2018 |
| Estimated completion | 30 June 2019 |
| Sites | 1 location across Czechia |
Drugs / interventions tested
- NIRS based protocol
Conditions studied
- Cognitive Dysfunction — all drugs for Cognitive Dysfunction →
- Patient Positioning — all drugs for Patient Positioning →
Sponsor
University Hospital Hradec Kralove
Who can join
Adults 18 to 75, any sex, with Cognitive Dysfunction or Patient Positioning. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The occurrence of postoperative cognitive dysfunction (POCD) might be related to intraoperative cerebral desaturation. Positioning for neurosurgical procedures are associated with head rotation, elevation, flexion or extention that may affect blood brain inflow and outflow. Anatomical variations of Willis circle could affect the cerebral blood flow in extreme head position with the development of cerebral ischemia or functional changes of brain. Investigators suppose that detection of cerebral tissue desaturation and its prompt correction could modify the occurence of POCD after these procedures.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03093311
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Cognitive Dysfunction
Currently open trials in the same condition.
- NCT07526740 — Brain Stimulation and Cognitive Training for MCI · NA · recruiting
- NCT07517237 — taVNS + CCT for Neurocognitive Rehab · NA · recruiting
- NCT07171450 — Cognitive Remediation · NA · recruiting
- NCT07418008 — The Liver Cirrhosis Cognitive Decline Scale (LiCCoS) · recruiting
- NCT07394504 — Effects of Turning Based Dual Task Training on Balance and Mild Cognitive Impairment in Diabetic Peripheral Neuropathy · NA · recruiting
Other University Hospital Hradec Kralove trials
Trials by the same sponsor.
- NCT07415655 — Modulation of Cerebral Ischemia by Albumin · Phase 2 · not yet recruiting
- NCT03644641 — The Influence of Prone Position for Spinal Surgery on Visual Acuity · NA · not yet recruiting
- NCT06894927 — Hearing Screening in Adults Over 50 Years Old · NA · enrolling by invitation
- NCT05399602 — The Role of Neurofilament Light (NfL) in Patients With Hydrocephalus · NA · completed
- NCT06083233 — Role of Brain Specific Biomarkers in Hydrocephalus · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03093311 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital Hradec Kralove
- Last refreshed: 1 October 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03093311.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing