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NCT03091842

Exercise Intervention in Targeting Adiposity and Inflammation With Movement to Improve Prognosis in Breast Cancer

Withdrawn NA Last updated 24 October 2019
What this trial tests

NA trial testing Exercise Intervention in Cancer Survivor. Withdrawn.

Timeline
29 July 2019
Primary endpoint
29 July 2024
29 July 2025

Quick facts

Lead sponsorUniversity of Southern California
PhaseNA
StatusWithdrawn
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposesupportive care
Start date29 July 2019
Primary completion29 July 2024
Estimated completion29 July 2025
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Southern California

Who can join

18 and older, female only, with Cancer Survivor or Central Obesity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This randomized phase II trial studies how well exercise intervention works in targeting adiposity and inflammation with movement to improve prognosis in stage I-III breast cancer survivors. Different types of exercise may reduce inflammation in fat tissue and minimize the risk of cancer recurrence related to being overweight or obese.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Body weight management in overweight and obese breast cancer survivors.
    Shaikh H, Bradhurst P, Ma LX, Tan SYC, et al · · 2020 · cited 66× · PMID 33305350 · DOI 10.1002/14651858.cd012110.pub2
  2. Epidemiology and biology of physical activity and cancer recurrence.
    Friedenreich CM, Shaw E, Neilson HK, Brenner DR. · · 2017 · cited 65× · PMID 28620703 · DOI 10.1007/s00109-017-1558-9
  3. Obesity and Breast Cancer: The Role of Crown-Like Structures in Breast Adipose Tissue in Tumor Progression, Prognosis, and Therapy.
    Faria SS, Corrêa LH, Heyn GS, de Sant'Ana LP, et al · · 2020 · cited 43× · PMID 32595986 · DOI 10.4048/jbc.2020.23.e35
  4. Targeting Adiposity and Inflammation With Movement to Improve Prognosis in Breast Cancer Survivors (The AIM Trial): Rationale, Design, and Methods.
    Kang DW, Wilson RL, Gonzalo-Encabo P, Norris MK, et al · · 2022 · cited 1× · PMID 35795051 · DOI 10.3389/fonc.2022.896995

Verify or expand the search:

Other trials of Exercise Intervention

Trials testing the same drug.

Other recruiting trials for Cancer Survivor

Currently open trials in the same condition.

Other University of Southern California trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing