Last reviewed · How we verify
NCT03090347
Effects of Dietary Nutrients on Liver and Adipose Tissue Metabolism
NA trial testing Overconsumption of specific dietary nutrient in NAFLD in 100 participants. Status unknown.
31 March 2023
Quick facts
| Lead sponsor | University of Oxford |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 100 |
| Start date | 1 March 2017 |
| Primary completion | 31 March 2023 |
| Estimated completion | 31 March 2023 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Overconsumption of specific dietary nutrient
Conditions studied
- NAFLD — all drugs for NAFLD →
- Nutrient; Excess — all drugs for Nutrient; Excess →
Sponsor
University of Oxford
Who can join
Adults 18 to 65, any sex, with NAFLD or Nutrient; Excess. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In health,adipose tissue stores fat from the diet. If the fat tissue stops storing dietary fat then this increases the chance of it being stored in the liver, which is related to increased risk of heart disease and type 2 diabetes. It has been suggested that having a diet high in sugars or certain fats, may cause the fat tissue and liver to change how they function; we would like to investigate this in detail.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
The influence of nutritional state on the fatty acid composition of circulating lipid fractions: implications for their use as biomarkers of dietary fat intake.
Parry SA, Rosqvist F, Peters S, Young RK, et al · · 2021 · cited 4× · PMID 34471486 · DOI 10.48101/ujms.v126.7649 -
Using total plasma triacylglycerol to assess hepatic <i>de novo</i> lipogenesis as an alternative to VLDL triacylglycerol.
Hodson L, Parry SA, Cornfield T, Charlton C, et al · · 2020 · cited 4× · PMID 32208800 · DOI 10.1080/03009734.2020.1739789
Verify or expand the search:
- PubMed search for NCT03090347
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03090347 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Oxford
- Last refreshed: 7 June 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03090347.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing