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NCT03090347

Effects of Dietary Nutrients on Liver and Adipose Tissue Metabolism

Status unknown NA Last updated 7 June 2022
What this trial tests

NA trial testing Overconsumption of specific dietary nutrient in NAFLD in 100 participants. Status unknown.

Timeline
1 March 2017
Primary endpoint
31 March 2023
31 March 2023

Quick facts

Lead sponsorUniversity of Oxford
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposebasic science
Enrollment100
Start date1 March 2017
Primary completion31 March 2023
Estimated completion31 March 2023
Sites1 location across United Kingdom

Drugs / interventions tested

Conditions studied

Sponsor

University of Oxford

Who can join

Adults 18 to 65, any sex, with NAFLD or Nutrient; Excess. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In health,adipose tissue stores fat from the diet. If the fat tissue stops storing dietary fat then this increases the chance of it being stored in the liver, which is related to increased risk of heart disease and type 2 diabetes. It has been suggested that having a diet high in sugars or certain fats, may cause the fat tissue and liver to change how they function; we would like to investigate this in detail.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. The influence of nutritional state on the fatty acid composition of circulating lipid fractions: implications for their use as biomarkers of dietary fat intake.
    Parry SA, Rosqvist F, Peters S, Young RK, et al · · 2021 · cited 4× · PMID 34471486 · DOI 10.48101/ujms.v126.7649
  2. Using total plasma triacylglycerol to assess hepatic <i>de novo</i> lipogenesis as an alternative to VLDL triacylglycerol.
    Hodson L, Parry SA, Cornfield T, Charlton C, et al · · 2020 · cited 4× · PMID 32208800 · DOI 10.1080/03009734.2020.1739789

Verify or expand the search:

Other recruiting trials for NAFLD

Currently open trials in the same condition.

Other University of Oxford trials

Trials by the same sponsor.

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Data sources for this page

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