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NCT03089255: EvaTIP
Assessment of the Impact of TIP Score on Thromboprophylaxis in Patients With Non-surgical Lower Leg Trauma.
trial in Lower Limb Injury in 196 participants. Completed in 30 January 2018.
15 January 2018
Quick facts
| Lead sponsor | University Hospital, Angers |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 196 |
| Start date | 3 April 2017 |
| Primary completion | 15 January 2018 |
| Estimated completion | 30 January 2018 |
| Sites | 1 location across France |
Conditions studied
- Lower Limb Injury — all drugs for Lower Limb Injury →
- Pulmonary Embolism — all drugs for Pulmonary Embolism →
- Venous Thromboses — all drugs for Venous Thromboses →
Sponsor
University Hospital, Angers
Who can join
18 and older, any sex, with Lower Limb Injury or Pulmonary Embolism. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Traumatic lesions are the leading causes of admission to the emergency center (39%), isolated non-surgical lower limbs trauma are in the foreground. Two recent meta-analyzes suggest the value of Low Molecular Weight Heparins (LMWH) which would reduce symptomatic Thromboembolism Events (TE) in patients with lower limb trauma. However, many recent studies conclude to the need of stratifying the TE risk according to the patient and the nature of his trauma to obtain an individualized therapeutic decision. The retrospectively established L-TRIP (cast) score allows stratification of the risk without taking into account the type of trauma. The TIP score (Trauma, Immobilization and Patient) was established by consensus of international experts via the Delphi method. We suggest that the application of the TIP score to rationalize indications of thromboprophylaxis in patients with isolated non-surgical trauma of a lower limb should reduce the rate of anticoagulation prescription without increasing the risk of symptomatic thromboembolic complications with a direct benefit for patients and medico-economic for the society.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Venous thromboembolism risk stratification for patients with lower limb trauma and cast or brace immobilization.
Douillet D, Nemeth B, Penaloza A, Le Gal G, et al · · 2019 · cited 14× · PMID 31220097 · DOI 10.1371/journal.pone.0217748 -
Abstract
· 2018
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Related trials
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Other University Hospital, Angers trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03089255 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Angers
- Last refreshed: 4 June 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03089255.
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