Study of HIV-Infected and Uninfected Pregnant Woman/Child Dyads in Gaborone, Botswana

NCT03088410 PHASE4 COMPLETED

The purpose of this study is to assess the early longitudinal metabolic effects including insulin sensitivity in HIV-exposed uninfected (HEU) children compared to HIV-unexposed uninfected (HUU) children; as well as to determine differences in the effects of neonatal zidovudine (AZT) vs. nevirapine (NVP) prophylaxis on early longitudinal changes in insulin sensitivity in the first 3 years of life.

Details

Lead sponsor	Ann & Robert H Lurie Children's Hospital of Chicago
Phase	PHASE4
Status	COMPLETED
Enrolment	495
Start date	Mon Aug 22 2016 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Thu Mar 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• HIV
• Insulin Sensitivity
• Diabetes Mellitus

Interventions

• Zidovudine
• Nevirapine

Countries

Botswana