NCT03086746 (VINDICATE-MI) is a clinical trial in Myocardial Infarction, sponsored by University of Leeds.

Who is sponsoring NCT03086746?

NCT03086746 is sponsored by University of Leeds.

What condition does NCT03086746 study?

NCT03086746 studies Myocardial Infarction, Heart Failure, Systolic.

Is NCT03086746 still recruiting?

NCT03086746 is currently status unknown. Last updated 3 May 2018.

Last reviewed 2018-05-03 · How we verify

NCT03086746: VINDICATE-MI

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

VItamin D as a Novel Determinant of Injurious Cardiac Remodelling After acuTE Myocardial Infarction

Status unknown Last updated 3 May 2018

What this trial tests

trial in Myocardial Infarction in 800 participants. Status unknown.

Timeline

1 April 2018

Primary endpoint
1 April 2020

1 June 2020

Quick facts

Lead sponsor	University of Leeds
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	800
Start date	1 April 2018
Primary completion	1 April 2020
Estimated completion	1 June 2020
Sites	1 location across United Kingdom

Conditions studied

Myocardial Infarction — all drugs for Myocardial Infarction →
Heart Failure, Systolic — all drugs for Heart Failure, Systolic →

Sponsor

University of Leeds

Who can join

18 and older, any sex, with Myocardial Infarction or Heart Failure, Systolic. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To provide insight into why vitamin D levels at baseline predict an adverse outcome including hospitalisation, we will establish whether baseline vitamin D levels are an independent marker of LV remodelling in patients experiencing an ST segment elevation myocardial infarction.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Vitamin D and Cardiovascular Disease: Current Evidence and Future Perspectives.
Cosentino N, Campodonico J, Milazzo V, De Metrio M, et al · · 2021 · cited 97× · PMID 34684604 · DOI 10.3390/nu13103603
Vitamin D and Cardiovascular Disease: The "Good", the "Bad", and the "Unknown".
Giamundo DM, Morello M, Pastena P, Bernardi M, et al · · 2025 · PMID 41209105 · DOI 10.31083/rcm40001

Verify or expand the search:

Other recruiting trials for Myocardial Infarction

Currently open trials in the same condition.

NCT07257198 — Aspirin-free Strategy With Ticagrelor in Patients With a Myocardial Infarction Treated Medically Alone · Phase 3 · recruiting
NCT07402642 — Effect of Early Educational Intervention on Cardiovascular Risk Factors After Acute Coronary Syndrome · NA · recruiting
NCT07301034 — A Research Study to Look at the Effect of Ziltivekimab on Plaque in the Blood Vessels of the Heart, Compared to Placebo, · Phase 3 · recruiting
NCT07142265 — Evaluation of 1-Year Clinical Outcomes With Early Inclisiran Initiation in Post-MI Patients · recruiting
NCT07138911 — Effect of Home-based Exercise Plan Mediated by Use of Digital Health App on Kinesiophobia and Functional Capacity · NA · recruiting

Other University of Leeds trials

Trials by the same sponsor.

NCT07488143 — AI-assisted Continuous Stratification in Neurorehabilitation of Stroke Using Personalized Digital Twins · NA · not yet recruiting
NCT07409363 — Non-invasive Vagus Nerve Stimulation for Chronic Musculoskeletal Pain · NA · not yet recruiting
NCT07247812 — tSCS in Children and Young People With HCP · NA · not yet recruiting
NCT07181915 — Changing Outcomes Through Achievement Emails in COPD Using Routine Healthcare Audits · NA · active not recruiting
NCT06240403 — Digoxin and Senolysis in Heart Failure and Diabetes Mellitus · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03086746 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Leeds
Last refreshed: 3 May 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03086746.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing