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NCT03083249
Gardasil Knowledge
trial testing Gardasil in HPV in 50 participants. Completed in 1 June 2018.
1 May 2018
Quick facts
| Lead sponsor | Sarah Hostetter, MD |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 1 February 2017 |
| Primary completion | 1 May 2018 |
| Estimated completion | 1 June 2018 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Gardasil — full drug profile →
Conditions studied
- HPV — all drugs for HPV →
Sponsor
Sarah Hostetter, MD
Who can join
Adults 18 to 26, female only, with HPV. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Human papillomavirus (HPV) is the most common viral genital tract infection. The majority of women and men who are sexually active will be exposed to a strain or strains of the virus. While there are hundreds of viral strains, high risk strains are associated cervical and oral cancers. According to the Centers for Disease Control (CDC), between 2008 and 2012 there were 38,793 deaths attributed to HPV related cancers. Vaccinations were created in an attempt to prevent infection from the most common high risks strains of HPV. Gardasil/HPV-9 was created to help prevent HPV related cancers and warts. The HPV-9 vaccine includes protection from 7 strains of HPV associated with 74% of HPV related cancers. While Gardasil was approved and released in 2006, many men and women have not been vaccinated. A national immunization survey in 2011 of teens 13-17 years old noted that only 60% of girls and 40% of boys have received at least one vaccination in the series. While complete vaccination series is recommended, a recent study found that a single dose of Gardasil when compared to placebo created a higher level of serum antibodies in uninfected females.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03083249
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Gardasil
Trials testing the same drug.
- NCT06142461 — Safety and Immunogenicity of HPV Vaccine Administered Intradermally and Intramuscularly Via Needle-Free Injection System · Phase 2 · withdrawn
- NCT04022148 — The Prospective Cohort Study to Evaluate the Preventive Efficacy of HPV Vaccine in Japanese Women Aged 27-45 Years · unknown
- NCT03998254 — Efficacy, Immunogenicity and Safety of V503 in Chinese Women Aged 20-45 Years (V503-023) · Phase 3 · active not recruiting
- NCT04453241 — Immunogenicity and Safety Study of NBP615 in Healthy Female · Phase 1, PHASE2 · completed
- NCT01914367 — Study of the Molecular Mechanisms Underlying the Cross-neutralizing Capacity of AS04-adjuvanted HPV Vaccine (Cervarix®) · Phase 4 · completed
Other recruiting trials for HPV
Currently open trials in the same condition.
- NCT07493928 — HPV After chemoRadioTherapy · recruiting
- NCT07065630 — Response-Adaptive Treatment in Untreated Locoregional HPV-Negative Head and Neck Cancer · Phase 2 · recruiting
- NCT06796738 — Advancing Cervical Cancer Screening Through the Emergency Department - IIS · NA · active not recruiting
- NCT07273383 — Self-sampling for HPV Screening · NA · active not recruiting
- NCT07438080 — Concordance and Acceptability of Self-screening Compared to Screening Carried Out by a Health Professional for HPV, a Ri · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03083249 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sarah Hostetter, MD
- Last refreshed: 6 June 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03083249.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing