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NCT03070067
SpecTRA; A Study of the Validation of Protein Biomarkers in Transient Ischemic Attack
trial testing Non-Interventional Study in TIA in 1,150 participants. Completed in 31 March 2017.
31 March 2017
Quick facts
| Lead sponsor | Andrew Penn |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 1,150 |
| Start date | 1 April 2015 |
| Primary completion | 31 March 2017 |
| Estimated completion | 31 March 2017 |
| Sites | 2 locations across Canada |
Drugs / interventions tested
- Non-Interventional Study (non-interventional-study) — full drug profile →
Conditions studied
- TIA — all drugs for TIA →
Sponsor
Andrew Penn
Who can join
19 and older, any sex, with TIA. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A clinical decision support rule/tool for classification of TIA/mimic that will enable rapid detection of ACVS in hyper-acute settings is being developed. Also under development is a multi-protein test using mass spectrometry (MS). This test will provide TIA results within an hour or two for a fraction of the price of neuroimaging. With guidance provided by this test at their disposal, physicians can inform patients whether they can go home safely or whether they need further testing. The right patients will receive the right treatment, reduce unwarranted imaging risks and costs, and reduce the burden of stroke. The Heart and Stroke Foundation will work to ensure that physicians, allied healthcare providers, the public and other stakeholders are aware of the outcomes and clinical impacts of this project. Further, work is being done to establish the mechanisms to develop a strong phenotype for TIA that includes medical imaging (MRI), cardiac monitoring, cognitive assessments, and surveillance of health outcomes for extended periods of time.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Systolic blood pressure as a predictor of transient ischemic attack/minor stroke in emergency department patients under age 80: a prospective cohort study.
Penn AM, Croteau NS, Votova K, Sedgwick C, et al · · 2019 · cited 6× · PMID 31653207 · DOI 10.1186/s12883-019-1466-4
Verify or expand the search:
- PubMed search for NCT03070067
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for TIA
Currently open trials in the same condition.
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Other Andrew Penn trials
Trials by the same sponsor.
- NCT03050099 — SpecTRA; An Observational Study of the Verification of Protein Biomarkers in Transient Ischemic Attack. · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03070067 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Andrew Penn
- Last refreshed: 18 August 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03070067.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing