Who is sponsoring NCT03069391?

NCT03069391 is sponsored by Union College, New York.

What drugs are being tested in NCT03069391?

Interventions in NCT03069391: physical exercise alone (PES) first, cognitive exercise alone (iCE) first, interactive Physical and Cognitive Exercise (iPACES™).

What condition does NCT03069391 study?

NCT03069391 studies Alzheimer Disease, Early Onset, MCI, Aging, Mild Cognitive Impairment, Neurocognitive Disorder, Cognitive Impairment, Cognitive Change.

Is NCT03069391 still recruiting?

NCT03069391 is currently status unknown. Last updated 31 March 2020.

Last reviewed 2020-03-31 · How we verify

NCT03069391: iPACES™

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Interactive Physical and Cognitive Exercise System

Status unknown NA Last updated 31 March 2020

What this trial tests

NA trial testing physical exercise alone (PES) first in Alzheimer Disease, Early Onset in 31 participants. Status unknown.

Timeline

4 March 2017

Primary endpoint
30 June 2022

30 June 2022

Quick facts

Lead sponsor	Union College, New York
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	non randomized
Design	crossover
Masking	none
Primary purpose	treatment
Enrollment	31
Start date	4 March 2017
Primary completion	30 June 2022
Estimated completion	30 June 2022
Sites	1 location across United States

Drugs / interventions tested

physical exercise alone (PES) first
cognitive exercise alone (iCE) first
interactive Physical and Cognitive Exercise (iPACES™)

Conditions studied

Alzheimer Disease, Early Onset — all drugs for Alzheimer Disease, Early Onset →
MCI — all drugs for MCI →
Aging — all drugs for Aging →
Mild Cognitive Impairment — all drugs for Mild Cognitive Impairment →

Sponsor

Union College, New York

Who can join

50 and older, any sex, with Alzheimer Disease, Early Onset or MCI. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is intended to clarify the benefits to brain health and thinking processes that result from different forms of exercise. In particular, this study will investigate the possible benefits of physical exercise (such as pedaling an under-table stationary elliptical) or mental exercise (such as playing a videogame on a portable tablet), or combining these activities together (as in the iPACES™ exergame).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

The Enhanced Interactive Physical and Cognitive Exercise System (iPACES<sup>TM</sup> v2.0): Pilot Clinical Trial of an In-Home iPad-Based Neuro-Exergame for Mild Cognitive Impairment (MCI).
Wall K, Stark J, Schillaci A, Saulnier ET, et al · · 2018 · cited 31× · PMID 30200183 · DOI 10.3390/jcm7090249
Exergaming for dementia and mild cognitive impairment.
Voinescu A, Papaioannou T, Petrini K, Stanton Fraser D. · · 2024 · cited 9× · PMID 39319863 · DOI 10.1002/14651858.cd013853.pub2

Verify or expand the search:

Other recruiting trials for Alzheimer Disease, Early Onset

Currently open trials in the same condition.

NCT06814730 — A Study to Assess THN391 in Subjects With Alzheimer's Disease · Phase 1 · recruiting
NCT06688968 — Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease · NA · recruiting
NCT06668610 — A Multifocal TDCS-EEG Protocol for Improving Symptoms of Mild Cognitive Impairment and Early Dementia · NA · recruiting
NCT06268886 — Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Partici · Phase 2 · active not recruiting
NCT05983575 — A Pivotal Study of LIPUS-Brain in Patients With Early Alzheimer's Disease · Phase 3 · active not recruiting

Other Union College, New York trials

Trials by the same sponsor.

NCT04118972 — In the Mirror: Functional Appreciated Bodies (IM FAB) · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03069391 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Union College, New York
Last refreshed: 31 March 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03069391.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing