NCT03061422 is a NA clinical trial of Xylitol in Dental Caries, sponsored by Cairo University.

Who is sponsoring NCT03061422?

NCT03061422 is sponsored by Cairo University.

What drugs are being tested in NCT03061422?

Interventions in NCT03061422: Xylitol, xylitol with bicarbonate, paraffin.

What condition does NCT03061422 study?

NCT03061422 studies Dental Caries.

Is NCT03061422 still recruiting?

NCT03061422 is currently status unknown. Last updated 24 February 2017.

Last reviewed 2017-02-24 · How we verify

NCT03061422

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Xylitol-Containing Chewing Gum With/Without Bicarbonate Versus Paraffin Pellet on Salivary pH

Status unknown NA Last updated 24 February 2017

What this trial tests

NA trial testing Xylitol in Dental Caries in 36 participants. Status unknown.

Timeline

3 March 2017

Primary endpoint
1 October 2017

30 November 2018

Quick facts

Lead sponsor	Cairo University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	prevention
Enrollment	36
Start date	3 March 2017
Primary completion	1 October 2017
Estimated completion	30 November 2018
Sites	1 location across Egypt

Drugs / interventions tested

Xylitol — full drug profile →
xylitol with bicarbonate
paraffin — full drug profile →

Conditions studied

Dental Caries — all drugs for Dental Caries →

Sponsor

Cairo University

Who can join

Adults 20 to 50, any sex, with Dental Caries. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

36 eligible participants will be randomly divided into three groups (n=12) according to the tested chewing gum (A), where (A1) represents participants exposed to xylitol chewing gum, (A2) represents participants exposed to bicarbonate and xylitol chewing gum and (A3) represents control group where participants are exposed to paraffin pellet chewing. The pH of saliva will be evaluated according to time in relation to the gum chewing (T) where (T0) represent the pH before chewing, (T1) represent 5 minutes after gum chewing at fixed time of the day (in the morning from 10 to 11 am). Direct benefit of the research to the human volunteer: It is important for high caries risk patients to decrease caries susceptibility as this will eventually decrease their dental treatments and subsequently the treatment cost. Scientific value and social benefits: This study will benefit the dentist as the main goal of a dentist is to prevent rather than cure. Also, it will decrease the restorative work carried out by dentist and save this time for educating more patients about caries prevention methods. Expected risk to the human subjects: Allergic reactions due to any of the components of the materials used which is rare to occur.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Xylitol

Trials testing the same drug.

NCT06799039 — Pilot Trial of Xylitol for C. Difficile De-Colonization in Patients With Inflammatory Bowel Disease · EARLY_PHASE1 · not yet recruiting
NCT05852587 — Xylitol Use for Decolonization of C. Difficile in Patients With IBD · Phase 1 · not yet recruiting
NCT05579639 — Xylitol BSI Multisite - Reduction of Bloodstream Infections From Oral Organisms in Pediatric Stem Cell Transplant · Phase 2 · recruiting
NCT05671965 — Effects of Oral Xylitol on Subsequent Energy Intake · NA · completed
NCT04585061 — A Novel Approach in Reducing Dental Pain and Anxiety of Pediatric Patient During Local Anesthesia. · NA · completed

Other recruiting trials for Dental Caries

Currently open trials in the same condition.

NCT06787261 — Involvement of Archaea in Carious Disease · NA · recruiting
NCT06753669 — Mothers' Action Project for Child Health · NA · recruiting
NCT07431463 — Effects of Different Remineralization Agents on the Progression of Non-Cavitated Approximal Carious Lesions in Primary T · NA · active not recruiting
NCT07134114 — Occlusal Impact of Hall Crowns in Primary Molars · NA · recruiting
NCT07181967 — SDF vs Fluoride Varnish for Streptococcus Mutans Reduction in Children · NA · recruiting

Other Cairo University trials

Trials by the same sponsor.

NCT04155528 — Effect of Music Therapy on Postoperative Health Outcomes · NA · not yet recruiting
NCT07363239 — CBCT-Based Safety Distance for Implant Placement Near the Inferior Alveolar Canal · not yet recruiting
NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03061422 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cairo University
Last refreshed: 24 February 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03061422.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing