NCT03061383: DH

Reduction of Dentine Hypersensitivity Using 8% Arginine Based Toothpaste and 8% Strontium Acetate Based Toothpaste (DH)

Status unknown NA Last updated 23 February 2017

What this trial tests

NA trial testing 8% Arginine based toothpaste in Dentin Hypersensitivity in 51 participants. Status unknown.

Timeline

3 March 2017

Primary endpoint
3 October 2018

30 November 2018

Quick facts

Lead sponsor	Cairo University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	51
Start date	3 March 2017
Primary completion	3 October 2018
Estimated completion	30 November 2018
Sites	1 location across Egypt

Drugs / interventions tested

• 8% Arginine based toothpaste
• 8% strontium acetate based toothpaste
• placebo

Conditions studied

• Dentin Hypersensitivity — all drugs for Dentin Hypersensitivity →

Sponsor

Cairo University

Who can join

Adults 18 to 35, any sex, with Dentin Hypersensitivity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a randomized, triple-blind, placebo-controlled study. 51 subjects with a confirmed diagnosis of dentin hypersensitivity were randomized to one of three treatments: Arginine based toothpaste, strontium acetate based toothpaste , or placebo. Treatment will be done at baseline then patients will use the toothpaste at home twice per day by using soft bristled tooth brush and the given dentifrice using modified stillmans method as explained by examiner. Standard test stimuli is calibrated short blast of air syringe, will be applied to sensitive dentin surfaces. Subjects recorded the intensity of sensitivity in response to stimulus on a visual analog scale at baseline, and after 1 week, 2 weeks and 3 months.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.