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NCT03059459
Effect of Atmospheric Pollution on Obstructive Lung Diseases
trial in Lung Diseases, Obstructive in 117 participants. Status unknown.
4 December 2018
Quick facts
| Lead sponsor | National Council of Scientific and Technical Research, Argentina |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 117 |
| Start date | 4 December 2015 |
| Primary completion | 4 December 2018 |
| Estimated completion | 4 December 2018 |
Conditions studied
- Lung Diseases, Obstructive — all drugs for Lung Diseases, Obstructive →
Sponsor
National Council of Scientific and Technical Research, Argentina
Who can join
18 and older, any sex, with Lung Diseases, Obstructive. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Several studies have demonstrated the association between atmospheric pollution and chronic respiratory diseases. The magnitude of this association and its dependence of local factors are still unknown in Argentina, particularly for obstructive lung diseases like asthma and chronic obstructive pulmonary disease (COPD). The objective of this study is to assess the effect of atmospheric pollution due to particulate matter (PM) on asthma and COPD exacerbations in adults. A prospective cohort study will be carried out in patients attending the pulmonary service of a public hospital located in San Nicolas, Buenos Aires province, Argentina. Patients will be followed for 12 months after recruitment. The outcome variables will be the frequency of hospitalizations or emergency department consults for asthma or COPD exacerbations and related conditions, and the impact of COPD on a person's life as measured by the COPD assessment test (CAT) questionnaire. The exposure will be the pollution level in the particular address, measuring PM10 concentrations with portable equipment. Other variables as air temperature, humidity, and individual patient risk factors will be considered as potential confounders or effect modifiers. The associations will be estimated through regression models, i.e. logistic and Poisson regressions and recurrent event survival analysis. The results of this study should provide elements to estimate the risk of chronic respiratory diseases associated with atmospheric pollution, and to evaluate strategies for risk assessment in the local community.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03059459 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Council of Scientific and Technical Research, Argentina
- Last refreshed: 25 January 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03059459.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing