Study of Parecoxib Versus Celecoxib Versus Oxycodone on Perioperative Pain Control of Transcatheter Chemoembolization Procedure for Patients With Hepatocelullar Carcinoma

NCT03059238 Phase 3 COMPLETED

This phase III, randomized, prospective clinical study, aiming to compare the analgesic effects of celecoxib, parecoxib, and oxycodone in patients with inoperable hepatic carcinoma undergoing TACE procedure in postoperative pain control.

Details

Lead sponsor	Sun Yat-sen University
Phase	Phase 3
Status	COMPLETED
Enrolment	213
Start date	2016-09
Completion	2019-03

Conditions

• Liver Cancer
• Pain Postoperative

Interventions

• Celecoxib 200mg oral capsule
• parecoxib sodium
• controlled-release oxycodone

Primary outcomes

• Pain score — 48 hours
  Self reported pain intensity using the numeric rating scale (NRS) (score of 0-10) after administration of the first dose of study medication.

Countries

China