NCT03058081 (AiRehab) is a NA clinical trial of High Flow nasal cannula in COPD Exacerbation, sponsored by Groupe Hospitalier du Havre.

Who is sponsoring NCT03058081?

NCT03058081 is sponsored by Groupe Hospitalier du Havre.

What drugs are being tested in NCT03058081?

Interventions in NCT03058081: High Flow nasal cannula.

What condition does NCT03058081 study?

NCT03058081 studies COPD Exacerbation.

Is NCT03058081 still recruiting?

NCT03058081 is currently completed. Last updated 20 June 2018.

Last reviewed 2018-06-20 · How we verify

NCT03058081: AiRehab

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of High Flow Nasal During Exercise in COPD Patients

Completed NA Last updated 20 June 2018

What this trial tests

NA trial testing High Flow nasal cannula in COPD Exacerbation in 19 participants. Completed in 18 June 2018.

Timeline

1 August 2017

Primary endpoint
18 June 2018

18 June 2018

Quick facts

Lead sponsor	Groupe Hospitalier du Havre
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	treatment
Enrollment	19
Start date	1 August 2017
Primary completion	18 June 2018
Estimated completion	18 June 2018
Sites	1 location across France

Drugs / interventions tested

High Flow nasal cannula

Conditions studied

COPD Exacerbation — all drugs for COPD Exacerbation →

Sponsor

Groupe Hospitalier du Havre

Who can join

Adults 35 to 80, any sex, with COPD Exacerbation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Early pulmonary rehabilitation is recommended after an episode of severe exacerbation of chronic obstructive pulmonary disease (COPD). However, its implementation is challenging particularly as regard exercise training. High flow ventilation in reducing work of breathing and dyspnea may improve exercise tolerance. The aim of this study is to carry out the acute effect of high flow nasal cannula on exercise endurance in post-exacerbation copd patients

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Nasal high flow does not improve exercise tolerance in COPD patients recovering from acute exacerbation: A randomized crossover study.
Prieur G, Medrinal C, Combret Y, Dupuis Lozeron E, et al · · 2019 · cited 18× · PMID 31387158 · DOI 10.1111/resp.13664
Efficiency of High-Flow Nasal Cannula on Pulmonary Rehabilitation in COPD Patients: A Meta-Analysis.
Fu C, Liu X, Zhu Q, Wu X, et al · · 2020 · cited 8× · PMID 33083481 · DOI 10.1155/2020/7097243
Effect of high-flow nasal therapy during acute aerobic exercise in patients with chronic obstructive pulmonary disease after exacerbation: protocol for a randomised, controlled, cross-over trial.
Prieur G, Medrinal C, Combret Y, Quesada AR, et al · · 2017 · cited 3× · PMID 29071072 · DOI 10.1136/bmjresp-2017-000191

Verify or expand the search:

Other trials of High Flow nasal cannula

Trials testing the same drug.

NCT04082208 — High Flow Nasal Cannula in Patients Undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP) HF-study · NA · unknown

Other recruiting trials for COPD Exacerbation

Currently open trials in the same condition.

NCT07351929 — Emotional-distress-based Integrated Care Programme in Patients With an Acute Exacerbation of COPD · NA · recruiting
NCT05703919 — Standard vs Targeted Oxygen Therapy Prehospital for Chronic Obstructive Pulmonary Disease · Phase 4 · recruiting
NCT06347536 — Supported Rescue Packs Post-discharge in Chronic Obstructive Pulmonary Disease · Phase 3 · recruiting
NCT06691399 — Role of Oral Care in Prevention of Nosocomial Pneumonia Among COPD Patients · NA · recruiting
NCT05958563 — Impact of Continuous Positive Airway Pressure on the Occurrence of Acute Exacerbations of COPD in Patients With COPD-OSA · NA · recruiting

Other Groupe Hospitalier du Havre trials

Trials by the same sponsor.

NCT07371754 — Shear Wave Elastography of Intercostal Muscles for the Non-invasive Assessment of the Work of BreathinG · not yet recruiting
NCT07492745 — Effect of Using a Reminder to Encourage Patients to be Active During Their Hospital Stay. · NA · recruiting
NCT06994689 — Clinimetric Properties of Muscle Mass and Stiffness Measurements of the Quadriceps in Patients With COPD · recruiting
NCT06249412 — The Importance of Positive Expiratory Pressure Associated With the In-exsufflator in ALS Patients · NA · recruiting
NCT06772701 — Validation of the French Version of the Edinburgh Postnatal Depression Scale (EPDS) Postnatally in the Father · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03058081 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Groupe Hospitalier du Havre
Last refreshed: 20 June 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03058081.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing