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NCT03055715

Prognostic Evaluation of Tumor Volume and Its Changes in Radical Radiotherapy of Advanced NSCLC

Completed Last updated 2 May 2018
What this trial tests

trial in Non Small Cell Lung Cancer Stage III in 346 participants. Completed in 1 April 2018.

Timeline
1 April 2017
Primary endpoint
1 April 2018
1 April 2018

Quick facts

Lead sponsorMartin-Luther-Universität Halle-Wittenberg
StatusCompleted
Study typeOBSERVATIONAL
Enrollment346
Start date1 April 2017
Primary completion1 April 2018
Estimated completion1 April 2018
Sites22 locations across Belgium, Austria, Germany, Switzerland, Spain

Conditions studied

Sponsor

Martin-Luther-Universität Halle-Wittenberg — full company profile →

Who can join

Adults 18 to 100, any sex, with Non Small Cell Lung Cancer Stage III. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the study is to retrospectively monitor the 'gross tumor volume' (GTV) before initiation of radiotherapy and its changes during radiotherapy and to correlate them with retrospectively recorded patient data, as well as with prognostic and therapeutic outcome after definite radiotherapy of locally advanced NSCLC in stage UICC III.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Prognostic impact of gross tumor volume during radical radiochemotherapy of locally advanced non-small cell lung cancer-results from the NCT03055715 multicenter cohort study of the Young DEGRO Trial Group.
    Ostheimer C, Mäurer M, Ebert N, Schmitt D, et al · · 2021 · cited 11× · PMID 33410959 · DOI 10.1007/s00066-020-01727-4
  2. PET/CT-based adaptive radiotherapy of locally advanced non-small cell lung cancer in multicenter yDEGRO ARO 2017-01 cohort study.
    Mäurer M, Käsmann L, Fleischmann DF, Oertel M, et al · · 2022 · cited 7× · PMID 35139856 · DOI 10.1186/s13014-022-01997-5
  3. Tumor volume change at radiation boost planning to estimate the response to chemoradiotherapy in stage III unresectable NSCLC (TORCH): a multicenter retrospective observational study.
    Trommer S, Müller JA, Oertel M, Ehret F, et al · · 2025 · cited 1× · PMID 40029351 · DOI 10.1007/s00066-025-02374-3
  4. Correction to: Prognostic impact of gross tumor volume during radical radiochemotherapy of locally advanced non-small cell lung cancer-results from the NCT03055715 multicenter cohort study of the Young DEGRO Trial Group.
    Ostheimer C, Mäurer M, Ebert N, Schmitt D, et al · · 2021 · cited 1× · PMID 33674905 · DOI 10.1007/s00066-021-01750-z
  5. Tenth anniversary of the Young DEGRO Team Trial-reflecting on the past, shaping the future.
    Ehret F, Oertel M, Rühle A. · · 2026 · PMID 40553141 · DOI 10.1007/s00066-025-02417-9

Verify or expand the search:

Other recruiting trials for Non Small Cell Lung Cancer Stage III

Currently open trials in the same condition.

Other Martin-Luther-Universität Halle-Wittenberg trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03055715.

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