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NCT03055247: XCGD-MOBI
Combination of Ibuprofen, G-CSF and Plerixafor as Stem Cells Mobilization Regimen in Patients Affected by X-CGD
Phase 2 trial testing Ibuprofen in Chronic Granulomatous Disease X-linked (X-CGD) in 3 participants. Currently enrolling.
13 July 2023
Quick facts
| Lead sponsor | IRCCS San Raffaele |
|---|---|
| Phase | Phase 2 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 3 |
| Start date | 6 November 2015 |
| Primary completion | 13 July 2023 |
| Estimated completion | 18 July 2026 |
| Sites | 2 locations across Italy |
Drugs / interventions tested
- Ibuprofen (ibuprofen) — full drug profile →
- Myelostim — full drug profile →
- Mozobil (plerixafor) — full drug profile →
Conditions studied
- Chronic Granulomatous Disease X-linked (X-CGD) — all drugs for Chronic Granulomatous Disease X-linked (X-CGD) →
Sponsor
IRCCS San Raffaele — full company profile →
Who can join
Adults 18 to 45, male only, with Chronic Granulomatous Disease X-linked (X-CGD). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a phase II exploratory study conducted to evaluate the safety and efficacy of the combination of Ibuprofen, G-CSF and Plerixafor as stem cell mobilization regimen in patients affected by X-CGD.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03055247
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03055247 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by IRCCS San Raffaele
- Last refreshed: 18 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03055247.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing