Who is sponsoring NCT03045185?

NCT03045185 is sponsored by University of Leeds.

What drugs are being tested in NCT03045185?

Interventions in NCT03045185: RET using Ciprofloxacin 100mg, and Metronidazole 100mg..

What condition does NCT03045185 study?

NCT03045185 studies Tooth Injuries, Endodontically Treated Teeth.

Is NCT03045185 still recruiting?

NCT03045185 is currently completed. Last updated 8 February 2017.

Last reviewed 2017-02-08 · How we verify

NCT03045185

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Regenerative Endodontic Treatment of Traumatised Teeth

Completed NA Last updated 8 February 2017

What this trial tests

NA trial testing RET using Ciprofloxacin 100mg, and Metronidazole 100mg. in Tooth Injuries in 15 participants. Completed in 1 January 2017.

Timeline

1 January 2013

Primary endpoint
1 January 2015

1 January 2017

Quick facts

Lead sponsor	University of Leeds
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	15
Start date	1 January 2013
Primary completion	1 January 2015
Estimated completion	1 January 2017

Drugs / interventions tested

RET using Ciprofloxacin 100mg, and Metronidazole 100mg.

Conditions studied

Tooth Injuries — all drugs for Tooth Injuries →
Endodontically Treated Teeth — all drugs for Endodontically Treated Teeth →

Sponsor

University of Leeds

Who can join

Adults 6 to 16, any sex, with Tooth Injuries or Endodontically Treated Teeth. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Aim: The aim of this prospective study was to evaluate the treatment outcomes of regenerative endodontic technique (RET) for the management of traumatised non-vital immature teeth in children. Methodology: This study aims to recruit 25-30 healthy children with traumatised non-vital immature upper incisors to be treated with bi-antibiotic regenerative endodontic technique. Patients will be reviewed clinically at 3m,6m,9m,12m,2y,and 3 years and radiographically at 3m,9m, 2y,and 3 years. One operator will undertake all treatments, clinical reviews and standardised radiographic exposures. Radiographic analysis will be carried out by two calibrated experienced clinicians. Standardised photographs will be taken at 3m,12m,2y,and 3 years and crown colour changes will be assessed using a standardised validated methodology.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Revitalisation endodontic treatment of traumatised immature teeth: a prospective long-term clinical study.
Nazzal H, Ainscough S, Kang J, Duggal MS. · · 2020 · cited 11× · PMID 31808111 · DOI 10.1007/s40368-019-00501-0

Verify or expand the search:

Other recruiting trials for Tooth Injuries

Currently open trials in the same condition.

NCT07309653 — Colour Match, Stability, and Patient's Satisfaction of Single-Shade Composites in Anterior Teeth · recruiting
NCT06406582 — Treatment Result of Zirconia Laminate Veneer · NA · recruiting

Other University of Leeds trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03045185 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Leeds
Last refreshed: 8 February 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03045185.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing