NCT03044938 is a Phase 4 clinical trial of salbutamol in Asthma, sponsored by Universidade Ibirapuera.

Who is sponsoring NCT03044938?

NCT03044938 is sponsored by Universidade Ibirapuera.

What drugs are being tested in NCT03044938?

Interventions in NCT03044938: salbutamol, Placebo.

What condition does NCT03044938 study?

NCT03044938 studies Asthma, Heart Rate Fast.

Is NCT03044938 still recruiting?

NCT03044938 is currently completed. Last updated 7 February 2017.

Last reviewed 2017-02-07 · How we verify

NCT03044938

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Acute Effect of Salbutamol on Heart Rate and Blood Pressure During Exercise in Patients With Moderate or Severe Asthma and Healthy Subjects

Completed Phase 4 Last updated 7 February 2017

What this trial tests

Phase 4 trial testing salbutamol in Asthma in 15 participants. Completed in 21 November 2016.

Timeline

6 August 2016

Primary endpoint
6 August 2016

21 November 2016

Quick facts

Lead sponsor	Universidade Ibirapuera
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	triple
Primary purpose	prevention
Enrollment	15
Start date	6 August 2016
Primary completion	6 August 2016
Estimated completion	21 November 2016
Sites	1 location across Brazil

Drugs / interventions tested

salbutamol (salbutamol) — full drug profile →
Placebo

Conditions studied

Asthma — all drugs for Asthma →
Heart Rate Fast — all drugs for Heart Rate Fast →

Sponsor

Universidade Ibirapuera

Who can join

Adults 20 to 59, any sex, with Asthma or Heart Rate Fast. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Contextualization: Exercise is a common triggers of bronchospasm in patients with asthma and healthy subjects. To prevent these symptoms frequently they have to use Short-Acting Beta2-Agonists. However, the cardiovascular effects of salbutamol during and after exercise remain poorly known. Objective: To evaluate the effect of salbutamol on heart rate and blood pressure during exercise in patients with moderate or severe asthma and healthy individuals. Methods: A randomized, double-blind, crossover study will be conducted which 13 individuals with moderate or severe persistent asthma and 13 healthy individuals aged between 20 to 59 years. Patients will perform a maximal effort test on 2 nonconsecutive days, with either 400mcg Salbutamol or 4 placebo puffs. The order of use of placebo or salbutamol will be drawn. During the protocol, heart rate, blood pressure, perception of exertion and peak expiratory flow will be monitored.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Role of adrenergic receptor signalling in neuroimmune communication.
Chhatar S, Lal G. · · 2021 · cited 76× · PMID 35492402 · DOI 10.1016/j.crimmu.2021.11.001

Verify or expand the search:

Other trials of salbutamol

Trials testing the same drug.

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NCT03902106 — Physiological Response to Salbutamol and Exercise · NA · unknown
NCT01687296 — Nebulized Fluticasone Propionate VS Oral Prednisone in Chinese Pediatric and Adolescent Subjects With an Acute Exacerbat · Phase 3 · completed

Other recruiting trials for Asthma

Currently open trials in the same condition.

NCT07525375 — A Phase II Study to Investigate Lung Function With 2 Different Doses of Inhaled Glycopyrronium Taken With BFF Compared t · Phase 2 · recruiting
NCT07536256 — Community Connections Through Native Hawaiian Cultural Values to Strengthen Youth Resilience, Health, and Well-Being · NA · recruiting
NCT07556159 — A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice · recruiting
NCT07282886 — VENTURI (VENTilation Using Respiratory Imaging) · Phase 2 · recruiting
NCT07433569 — A Study to Investigate How Budesonide and Formoterol Move Through the Body (Pharmacokinetics) When Delivered With Differ · Phase 1 · recruiting

Other Universidade Ibirapuera trials

Trials by the same sponsor.

NCT03827889 — Efficacy of Two Protocols for Applying Fluorine Varnish to Deciduous Teeth · NA · suspended
NCT03785769 — Pre-etching of Dentin Before Restorations With High Viscosity Glass Ionomer Cement · NA · withdrawn
NCT03785730 — Non-restorative Cavity Control in Anterior Cavitated Caries Lesion of Primary Teeth · NA · suspended
NCT04013659 — Effect of Gel Renewal During In-office Dental Bleaching · Phase 1 · unknown
NCT03812965 — Botulinum Toxin in the Treatment of Gingival Smile · Phase 2 · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03044938 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universidade Ibirapuera
Last refreshed: 7 February 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03044938.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing