NCT03034733 is a Phase 4 clinical trial of Dexamethasone in Arthroplasty, Knee Replacement, sponsored by University of Oulu.

Who is sponsoring NCT03034733?

NCT03034733 is sponsored by University of Oulu.

What drugs are being tested in NCT03034733?

Interventions in NCT03034733: Dexamethasone, Sodium Chloride, (24)NaCl 0,9%.

What condition does NCT03034733 study?

NCT03034733 studies Arthroplasty, Knee Replacement, Pain, Postoperative.

Is NCT03034733 still recruiting?

NCT03034733 is currently terminated. Last updated 29 November 2018.

Last reviewed 2018-11-29 · How we verify

NCT03034733

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of Dexamethasone on Pain After Total Knee Replacement Surgery

Terminated Phase 4 Last updated 29 November 2018

What this trial tests

Phase 4 trial testing Dexamethasone in Arthroplasty, Knee Replacement in 27 participants. Terminated before completion.

Timeline

15 February 2017

Primary endpoint
31 January 2018

31 January 2018

Quick facts

Lead sponsor	University of Oulu
Phase	Phase 4
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	27
Start date	15 February 2017
Primary completion	31 January 2018
Estimated completion	31 January 2018
Sites	1 location across Finland

Drugs / interventions tested

Dexamethasone (dexamethasone) — full drug profile →
Sodium Chloride, (24)NaCl 0,9% — full drug profile →

Conditions studied

Arthroplasty, Knee Replacement — all drugs for Arthroplasty, Knee Replacement →
Pain, Postoperative — all drugs for Pain, Postoperative →

Sponsor

University of Oulu

Who can join

Adults 18 to 90, any sex, with Arthroplasty, Knee Replacement or Pain, Postoperative. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to examine, if a single-dose of dexamethasone given during the operation, alleviates pain after knee replacement surgery.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis.
Weibel S, Rücker G, Eberhart LH, Pace NL, et al · · 2020 · cited 125× · PMID 33075160 · DOI 10.1002/14651858.cd012859.pub2

Verify or expand the search:

Other trials of Dexamethasone

Trials testing the same drug.

NCT07543458 — Therapeutics for Moderate and Severe Dengue · Phase 3 · not yet recruiting
NCT07175415 — HEM-iSMART E: Capivasertib + Venetoclax + Dexamethasone in Pediatric Patients With Relapsed or Refractory Hematological · Phase 1, PHASE2 · not yet recruiting
NCT07513129 — A Phase 1 Study Of Venetoclax, Dexamethasone, Bortezomib, And Daratumumab (VDBD) For Adolescent And Young Adult Patients · Phase 1 · not yet recruiting
NCT07444710 — Testing the Addition of an Anti-Cancer Drug, Glofitamab, to the Usual Chemotherapy Treatment (Alternating R-CHOP/R-DHAP) · Phase 1 · not yet recruiting
NCT07387926 — Safety and Efficacy of Asciminib in Pediatrics and Young Adults With Relapse/Refractory (r/r) Philadelphia Positive (Ph+ · Phase 1, PHASE2 · not yet recruiting

Other University of Oulu trials

Trials by the same sponsor.

NCT07381933 — The Effect of Consumed Berries on Extracellular Vesicle Signalling in the Body · NA · recruiting
NCT07280624 — Diagnostic PCR Panel in Children With Acute Gastrointestinal Symptoms · NA · not yet recruiting
NCT05494684 — Effectiveness of Multisensoral Nature-based Intervention in Hospitalized Children During Venous Blood Sampling · NA · not yet recruiting
NCT06711393 — The Effectiveness of Exergaming for Older People Mobility and Balance · NA · not yet recruiting
NCT06171867 — PNEUMACRIT Device for Neonatal Cardio Respiratory Monitoring · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03034733 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Oulu
Last refreshed: 29 November 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03034733.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing