NCT03027583 is a NA clinical trial of Probiotic in Intestinal Permeability, sponsored by Chr Hansen.

Who is sponsoring NCT03027583?

NCT03027583 is sponsored by Chr Hansen.

What drugs are being tested in NCT03027583?

Interventions in NCT03027583: Probiotic, Placebo.

What condition does NCT03027583 study?

NCT03027583 studies Intestinal Permeability.

Is NCT03027583 still recruiting?

NCT03027583 is currently completed. Last updated 3 May 2018.

Last reviewed 2018-05-03 · How we verify

NCT03027583

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of Probiotic Intervention on Intestinal Permeability

Completed NA Last updated 3 May 2018

What this trial tests

NA trial testing Probiotic in Intestinal Permeability in 251 participants. Completed in 15 September 2017.

Timeline

1 March 2017

Primary endpoint
30 July 2017

15 September 2017

Quick facts

Lead sponsor	Chr Hansen
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	prevention
Enrollment	251
Start date	1 March 2017
Primary completion	30 July 2017
Estimated completion	15 September 2017
Sites	1 location across Ireland

Drugs / interventions tested

Probiotic
Placebo

Conditions studied

Intestinal Permeability — all drugs for Intestinal Permeability →

Sponsor

Chr Hansen — full company profile →

Who can join

Adults 18 to 50, any sex, with Intestinal Permeability. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This trial is a single-site, randomised, double blind, placebo-controlled, two-armed parallel-group trial in healthy adult volunteers. The trial will investigate the effect of oral supplementation of a probiotic strain on the ability to attenuate exercise-induced deterioration of intestinal barrier function and gastrointestinal symptoms.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Safety of <i>Bifidobacterium breve</i>, Bif195, employing a human exercise-induced intestinal permeability model: a randomised, double-blinded, placebo-controlled, parallel group trial.
Engel S, Mortensen B, Wellejus A, Vera-Jimenez N, et al · · 2022 · cited 8× · PMID 35866597 · DOI 10.3920/bm2021.0173

Verify or expand the search:

Other trials of Probiotic

Trials testing the same drug.

NCT07529457 — Akk09 in Adults With Constipation · NA · not yet recruiting
NCT07507955 — Probiotics for Constipation Relief in Adults · NA · not yet recruiting
NCT07462481 — Probiotic Improve Constipation · NA · recruiting
NCT07511855 — Stress-buffering and Sleep Disturbance-resilient Effects of a Dual Bifidobacterium Longum Combination Under Short-term T · Phase 2 · not yet recruiting
NCT07474064 — Probiotics Combined With Targeted Therapy Plus Immunotherapy in Bladder-Preserving Setting for Patients With MIBC · Phase 2 · not yet recruiting

Other recruiting trials for Intestinal Permeability

Currently open trials in the same condition.

NCT04083950 — Induction of Gut Permeability by an Oral Vaccine · EARLY_PHASE1 · active not recruiting

Other Chr Hansen trials

Trials by the same sponsor.

NCT05840978 — Effect of Probiotics on Stress in Young Adults · NA · completed
NCT05564767 — Effect of Two Probiotic Formulations on Mental Health and Mood Biomarkers in Adults With Depressive Symptoms · NA · completed
NCT05529693 — Efficacy of a Probiotic Strain on Level of Markers of Inflammation in an Elderly Population · NA · completed
NCT04987593 — Characterisation of the Gut Microbiota in Term Infants After Maternal Supplementation of Probiotics · NA · completed
NCT04994834 — Characterization of the Gastrointestinal Microbiota in Term Newborn Infants After 4 Weeks Supplementation of Probiotics · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03027583 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Chr Hansen
Last refreshed: 3 May 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03027583.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing