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Diagnosis of Adult Growth Hormone Deficiency With Growth Hormone Releasing Hormone Plus Arginine Stimulation Test
The purpose of this study was to validate the growth hormone releasing hormone (GHRH) plus arginine (GHRH+arg) stimulation test and it´s cut-off limits for diagnosis of adult growth hormone deficiency using the growth hormone (GH) Immulite 2000 Xpi assay calibrated against the IS 98/574 from the World Health Organization. A specific aim was to study the effect of gender and age on the peak GH response in the GHRH+arg test
Details
| Lead sponsor | Helsinki University Central Hospital |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 160 |
| Start date | 2001-05 |
| Completion | 2008-12 |
Conditions
- Growth Hormone Deficiency
Interventions
- GHRH plus arginine test
Primary outcomes
- Peak serum GH (ug/l) by Immulite 2000 Xpi — one year
Countries
Finland