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Double Blind Randomized Trial of the Anti-Progestational Agent Mifepristone In The Treatment of Unresectable Meningioma
To compare daily oral mifepristone vs placebo with respect to time to treatment failure in patients with unresectable meningioma.
Details
| Lead sponsor | SWOG Cancer Research Network |
|---|---|
| Phase | Phase 3 |
| Status | COMPLETED |
| Enrolment | 193 |
| Start date | 1992-08 |
| Completion | 2012-11 |
Conditions
- Meningioma
Interventions
- Mifepristone
- Placebo
Primary outcomes
- Time to Treatment Failure — 6 years
From date of registration to first date of documentation of one of the following: 1. Progression (clear worsening of evaluable disease must be confirmed by 2 investigators). 2. Significant deterioration of at least one neurologic symptom 3. Discontinuation of treatment for any reason. 4. Death from any cause.