Genotype-tailored Treatment of Symptomatic Acid-Reflux in Children With Uncontrolled Asthma (GenARA)

NCT03015610 PHASE3 COMPLETED Results posted

This study will evaluate the effect of CYP2C19 and ABCB1 genes on pharmacokinetics of lansoprazole in children with mild gastroesophageal reflux (GER) and uncontrolled asthma. It will determine if genotype-guided lansoprazole dosing of lansoprazole improves GER and asthma control.

Details

Lead sponsor	Jason Lang, M.D., M.P.H.
Phase	PHASE3
Status	COMPLETED
Enrolment	41
Start date	Tue Oct 31 2017 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Thu Jan 18 2024 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Asthma
• Gastroesophageal Reflux

Interventions

• commercially available lansoprazole
• matched placebo

Countries

United States