NCT03012945 is a NA clinical trial of Combined epidural-general anesthesia in Elderly, sponsored by Peking University First Hospital.

Who is sponsoring NCT03012945?

NCT03012945 is sponsored by Peking University First Hospital.

What drugs are being tested in NCT03012945?

Interventions in NCT03012945: Combined epidural-general anesthesia, General anesthesia.

What condition does NCT03012945 study?

NCT03012945 studies Elderly, Malignant Tumor, Surgical Resection, Epidural Anesthesia, Long-term Outcome.

Is NCT03012945 still recruiting?

NCT03012945 is currently completed. Last updated 8 July 2020.

Last reviewed 2020-07-08 · How we verify

NCT03012945

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Epidural Anesthesia-analgesia and Long-term Outcome

Completed NA Last updated 8 July 2020

What this trial tests

NA trial testing Combined epidural-general anesthesia in Elderly in 1,802 participants. Completed in 30 September 2019.

Timeline

1 November 2014

Primary endpoint
30 September 2019

30 September 2019

Quick facts

Lead sponsor	Peking University First Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	1,802
Start date	1 November 2014
Primary completion	30 September 2019
Estimated completion	30 September 2019
Sites	5 locations across China

Drugs / interventions tested

Combined epidural-general anesthesia — full drug profile →
General anesthesia — full drug profile →

Conditions studied

Elderly — all drugs for Elderly →
Malignant Tumor — all drugs for Malignant Tumor →
Surgical Resection — all drugs for Surgical Resection →
Epidural Anesthesia — all drugs for Epidural Anesthesia →

Sponsor

Peking University First Hospital

Who can join

Adults 60 to 90, any sex, with Elderly or Malignant Tumor. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Surgical resection is one of the most important treatments for resectable cancer; on the other hand, cancer recurrence and/or metastasis are the major reasons of treatment failure. The development of recurrence/metastasis after cancer surgery mostly depends on the balance between the immunity of human body and the capability of implantation, proliferation and neovascularization of the residual cancer. Preclinical and retrospective clinical studies suggest that anaesthetic management may affect the long-term outcomes after cancer surgery. The investigators hypothesize that use of epidural anesthesia-analgesia may improve long-term survival in elderly patients after major surgery for cancer.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Intensive Care Unit admission and long-term survival in older patients after elective major noncardiac surgery: A secondary analysis.
Wu YJ, Li YW, Chen NP, Li M, et al · · 2025 · PMID 41379869 · DOI 10.1371/journal.pone.0338334

Verify or expand the search:

Other trials of Combined epidural-general anesthesia

Trials testing the same drug.

NCT03335826 — Epidural Anesthesia and Long-term Outcomes in Elderly Patients After Surgery · NA · completed
NCT02801409 — Epidural Anesthesia-analgesia and Long-term Survival After Lung Cancer Surgery · NA · completed

Other recruiting trials for Elderly

Currently open trials in the same condition.

NCT07494110 — Aurora: AI-Based Narrative Intervention to Support Emotional Well-Being in Clinical and Non-Clinical Populations · NA · recruiting
NCT07479147 — SENIOR: Stroke Prevention in the Elderly by Patent Foramen Ovale closuRe vs Anticoagulation · recruiting
NCT07509333 — MDT-Based Umbrella Decision Model for Geriatric Lung Cancer Patients · NA · recruiting
NCT07309965 — Feasibility of Integrating Local Vibration Into Rehabilitation of Elderly Patients After Hip Fracture · NA · recruiting
NCT07521189 — Effect of Vegetarien Diet on Protein Digestibility in Young and Elderly Volunteers · NA · recruiting

Other Peking University First Hospital trials

Trials by the same sponsor.

NCT07498907 — Disitamab Vedotin Plus Radiotherapy for Adjuvant Treatment of HER2-Expressing Cisplatin-Ineligible Upper Tract Urothelia · Phase 2 · not yet recruiting
NCT07517276 — TUDCA in High-Risk Lactating Mothers Identified by Early Postpartum Milk Hydrophobicity Index · Phase 2 · not yet recruiting
NCT07504939 — Multimodal Kidney-Sparing Strategy for High-Risk Upper Tract Urothelial Carcinoma · not yet recruiting
NCT07464119 — A Clinical Study of iPSC-Derived Islet Cells for Diabetes Mellitus Therapy · NA · not yet recruiting
NCT07460843 — Comparison of TB+PB and TB+6SB for Prostate Cancer Diagnosis · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03012945 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Peking University First Hospital
Last refreshed: 8 July 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03012945.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing