Adults 12 to 17, any sex, with Sexual Risk Behavior or Drug Use. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
Change in Drug UsePrimary· Baseline, Baseline to 6 months, baseline to 12 months, baseline to 24 months, baseline to 36 months
Change in drug use will be reported as the episodes of reported drug use for the previous 90 days with questions from Monitoring the Future
Baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care
.02
± .22
Treatment as Usual
.50
± 4.33
6 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care
.09
± .69
Treatment as Usual
.34
± 3.60
12 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care
.07
± .58
Treatment as Usual
.59
± 4.16
24 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care
.12
± .73
Treatment as Usual
1.46
± 9.03
36 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care
.22
± 1.78
Treatment as Usual
1.09
± 8.11
Change in Unprotected Sexual BehaviorPrimary· Baseline, Baseline to 6 months, baseline to 12 months, baseline to 24 months, baseline to 36 months
Change in unprotected sexual behavior was reported as endorsement incidence of having had sex without a condom during the previous 90 days using the Sexual Behavior Instrument. Higher values indicate worst outcomes.
Baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care
.04
± .39
Treatment as Usual
.08
± .50
6 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care
.04
± .33
Treatment as Usual
.08
± .50
12 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care
.05
± .43
Treatment as Usual
.09
± .56
24 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care
.13
± .66
Treatment as Usual
.19
± .78
36 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care
.28
± .89
Treatment as Usual
.21
± .81
Change in Family Functioning as Assessed by the Parenting Practices QuestionnaireSecondary· Baseline, Baseline to 6 months, baseline to 12 months, baseline to 24 months, baseline to 36 months
Change in family functioning will be reported using the Parenting Practices Scale (Tolan et al., 1997). Subscales include positive parenting (9 items, alpha = .78 for adolescents; alpha = .77 for parents) parental involvement( 20 items, alpha = .86 for adolescents; alpha = .85 parents). Responses range from 0 to 4 with higher values indicating better parenting, higher scores indicate more positive outcomes. The mean for each subscale was used to create a sum score.
Baseline positive parenting
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
23.66
± 4.9
Treatment as Usual-Parent
24.08
± 4.85
eHealth Familias Unidas Primary Care-Adolescent
21.9
± 6.02
Treatment as Usual-Adolescent
22.64
± 6.54
6 month positive parenting
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
23.83
± 4.75
Treatment as Usual-Parent
23.45
± 5.0
eHealth Familias Unidas Primary Care-Adolescent
22.10
± 6.02
Treatment as Usual-Adolescent
22.10
± 5.88
12 month positive parenting
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
23.85
± 4.72
Treatment as Usual-Parent
23.32
± 4.67
eHealth Familias Unidas Primary Care-Adolescent
22.09
± 5.98
Treatment as Usual-Adolescent
22.36
± 6.05
24 months positive parenting
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
23.71
± 4.73
Treatment as Usual-Parent
23.26
± 5.27
eHealth Familias Unidas Primary Care-Adolescent
21.78
± 6.42
Treatment as Usual-Adolescent
21.67
± 6.38
36 month positive parenting
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
22.50
± 5.17
Treatment as Usual-Parent
22.81
± 4.92
eHealth Familias Unidas Primary Care-Adolescent
21.89
± 6.46
Treatment as Usual-Adolescent
22.17
± 6.56
baseline parental involvement
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
50.49
± 8.40
Treatment as Usual-Parent
51.60
± 7.94
eHealth Familias Unidas Primary Care-Adolescent
41.98
± 9.60
Treatment as Usual-Adolescent
42.19
± 9.23
6 month parental involvement
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
50.66
± 7.93
Treatment as Usual-Parent
50.54
± 7.54
eHealth Familias Unidas Primary Care-Adolescent
41.62
± 9.01
Treatment as Usual-Adolescent
41.62
± 9.30
12 month parental involvement
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
50.71
± 8.53
Treatment as Usual-Parent
50.24
± 8.40
eHealth Familias Unidas Primary Care-Adolescent
41.81
± 9.16
Treatment as Usual-Adolescent
41.35
± 8.90
Change in Family Functioning as Assessed by the Parent Relationship With Peer GroupSecondary· Baseline, Baseline to 6 months, baseline to 12 months, baseline to 24 months, baseline to 36 months
Change in family functioning will be reported using the Parent Relationship with Peer Group. The Parent Relationship with Peer Group is a six item measure with response items ranging from 0 to 24. Higher scores indicate better outcomes.The mean was used to create a sum score.
Baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
11.90
± 4.2
Treatment as Usual-Parent
11.67
± 4.49
eHealth Familias Unidas Primary Care-Adolescent
9.67
± 4.6
Treatment as Usual-Adolescent
9.42
± 4.46
6 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
11.90
± 4.33
Treatment as Usual-Parent
11.87
± 4.33
eHealth Familias Unidas Primary Care-Adolescent
9.77
± 4.36
Treatment as Usual-Adolescent
8.93
± 4.59
12 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
11.92
± 4.36
Treatment as Usual-Parent
11.88
± 4.09
eHealth Familias Unidas Primary Care-Adolescent
9.56
± 4.70
Treatment as Usual-Adolescent
8.95
± 4.85
24 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
11.59
± 4.26
Treatment as Usual-Parent
11.78
± 4.31
eHealth Familias Unidas Primary Care-Adolescent
9.44
± 4.63
Treatment as Usual-Adolescent
8.96
± 4.58
36 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
11.25
± 4.39
Treatment as Usual-Parent
10.70
± 4.3
eHealth Familias Unidas Primary Care-Adolescent
9.06
± 4.64
Treatment as Usual-Adolescent
8.25
± 4.67
Change in Family Functioning as Assessed by the Parent-Adolescent Communication ScaleSecondary· Baseline, Baseline to 6 months, baseline to 12 months, baseline to 24 months, baseline to 36 months
Change in family functioning will be reported using the Parent-Adolescent Communication Scale. The Parent-Adolescent Communication Scale is a twenty-item questionnaire with a total score ranging from 20 to 100 with higher scores indicating better communication.The mean was used to create a sum score.
Baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
76.28
± 9.92
Treatment as Usual-Parent
76.29
± 10.36
eHealth Familias Unidas Primary Care-Adolescent
71.47
± 13.61
Treatment as Usual-Adolescent
71.67
± 13.3
6 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
77.55
± 10.00
Treatment as Usual-Parent
77.64
± 10.44
eHealth Familias Unidas Primary Care-Adolescent
72.87
± 14.75
Treatment as Usual-Adolescent
71.99
± 15.01
12 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
78.15
± 9.44
Treatment as Usual-Parent
77.10
± 11.11
eHealth Familias Unidas Primary Care-Adolescent
72.31
± 13.21
Treatment as Usual-Adolescent
71.39
± 15.03
24 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
79.85
± 10.18
Treatment as Usual-Parent
77.46
± 11.95
eHealth Familias Unidas Primary Care-Adolescent
71.66
± 14.40
Treatment as Usual-Adolescent
70.84
± 15.04
36 months post baseline
Group
Value
95% CI
eHealth Familias Unidas Primary Care-Parent
79.52
± 10.74
Treatment as Usual-Parent
77.70
± 11.47
eHealth Familias Unidas Primary Care-Adolescent
70.57
± 16.27
Treatment as Usual-Adolescent
69.63
± 15.80
Sponsor's own description
The purpose of this study is to test the relative effectiveness of a Hispanic-specific eHealth intervention, "e-Health Familias Unidas," in preventing and reducing drug use, sexual risk behaviors, and STIs among Hispanic youth in primary care. Families will be recruited through four pediatric primary care settings. Pediatric staff and research team members, including nurse assistants and mental health professionals, will implement eHealth Familias Unidas.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
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Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Miami
Last refreshed: 13 June 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03009539.