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Effects of Delta-9 Tetrahydrocannabinol (THC) on Retention of Memory for Fear Extinction Learning in PTSD: R61 Study
The goal of this study is to look at how a type of drug called cannabinoids are related to the processing of fear signals, the experience of emotions and fear, and the pattern of activity in the brain that is involved in these processes and how this relates to the development of post-traumatic stress disorder (PTSD). PTSD is an anxiety disorder that occurs after experiencing a traumatic event(s) and is characterized by unwanted memories of the trauma(s) through flashbacks or nightmares, avoidance of situations that remind the person of the event, difficulty experiencing emotions, loss of interest in activities the person used to enjoy, and increased arousal, such as difficulty falling asleep or staying asleep, anger and hypervigilance. The information gained from this study could lead to the development of new treatments for persons who suffer from anxiety or fear-based disorders.
Details
| Lead sponsor | Wayne State University |
|---|---|
| Phase | PHASE4 |
| Status | COMPLETED |
| Enrolment | 46 |
| Start date | Thu Jun 01 2017 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Tue Dec 31 2019 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- PostTraumatic Stress Disorder
Interventions
- Placebo Oral Capsule
- Dronabinol Cap 5 milligrams (MG)
- Dronabinol Cap 10 milligrams (MG)
Countries
United States