Pretreatment With Ablative Fractional Laser and Microdermabrasion Before Photodynamic Therapy for Actinic Keratoses in Field-cancerized Skin

NCT03006185 Phase 2 COMPLETED Results posted

Comparison of treatment efficacy and safety of pretreatment with ablative fractional laser versus microdermabrasion combined with large-area photodynamic therapy with methyl aminolevulinate for actinic keratoses

Details

Lead sponsor	Bispebjerg Hospital
Phase	Phase 2
Status	COMPLETED
Enrolment	18
Start date	2016-08
Completion	2017-03-01

Conditions

• Actinic Keratosis
• Sun Damaged Skin
• Solar Keratosis
• Solar Skin Damage

Interventions

• Ablative Fractional Carbon Dioxide (CO2) Laser
• Microdermabrasion

Primary outcomes

• Complete Clearance (%) of Actinic Keratoses (AKs) — 12-15 weeks post-treatment
  Percentage clearance of baseline actinic keratoses (AKs), determined by the ratio of AK lesions that are clinically resolved 12-15 weeks after treatment compared to the AK number at baseline.