NCT02999321 is a NA clinical trial of aspartame in Oral Glucose Tolerance, sponsored by Purdue University.

Who is sponsoring NCT02999321?

NCT02999321 is sponsored by Purdue University.

What drugs are being tested in NCT02999321?

Interventions in NCT02999321: aspartame, water.

What condition does NCT02999321 study?

NCT02999321 studies Oral Glucose Tolerance.

Is NCT02999321 still recruiting?

NCT02999321 is currently completed. Last updated 18 January 2018.

Last reviewed 2018-01-18 · How we verify

NCT02999321

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effects of Aspartame on Appetite, Body Composition and Oral Glucose Tolerance

Completed NA Last updated 18 January 2018

What this trial tests

NA trial testing aspartame in Oral Glucose Tolerance in 93 participants. Completed in 5 May 2017.

Timeline

17 August 2016

Primary endpoint
5 May 2017

5 May 2017

Quick facts

Lead sponsor	Purdue University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	basic science
Enrollment	93
Start date	17 August 2016
Primary completion	5 May 2017
Estimated completion	5 May 2017
Sites	1 location across United States

Drugs / interventions tested

aspartame (ASPARTAME) — full drug profile →
water (WATER) — full drug profile →

Conditions studied

Oral Glucose Tolerance — all drugs for Oral Glucose Tolerance →

Sponsor

Purdue University

Who can join

Adults 18 to 60, any sex, with Oral Glucose Tolerance. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Assess the impact of chronic use of aspartame on glycemia, appetite and body composition.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Aspartame Consumption for 12 Weeks Does Not Affect Glycemia, Appetite, or Body Weight of Healthy, Lean Adults in a Randomized Controlled Trial.
Higgins KA, Considine RV, Mattes RD. · · 2018 · cited 33× · PMID 29659969 · DOI 10.1093/jn/nxy021

Verify or expand the search:

Other recruiting trials for Oral Glucose Tolerance

Currently open trials in the same condition.

NCT05337098 — Non-Nutritive Sweetener Consumption and Glucose Homeostasis in Older Adults With Prediabetes · NA · recruiting

Other Purdue University trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02999321 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Purdue University
Last refreshed: 18 January 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02999321.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing