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Functional Magnetic Resonance Imaging of N-acetylcysteine in Cocaine Dependence
The objective of this research is to identify the functional neural mechanisms (as assessed using fMRI) of short-term N-acetylcysteine (NAC) administration among methadone-maintained individuals with cocaine dependence.
Details
| Lead sponsor | Yale University |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | COMPLETED |
| Enrolment | 21 |
| Start date | 2016-05 |
| Completion | 2020-09 |
Conditions
- Cocaine Dependence
Interventions
- N-acetylcysteine
- Placebo
Primary outcomes
- Change in neural network engagement measured using functional magnetic resonance imaging — 4 weeks
The primary outcome measure for this study is change (NAC versus placebo) in neural network engagement during fMRI task performance.
Countries
United States