Last reviewed · How we verify
NCT02990598: HELPS
Hydoxyurea Exposure in Lactation A Pharmacokinetics Study (HELPS)
trial in Sickle Cell Anemia in 16 participants. Completed in 19 June 2018.
19 June 2018
Quick facts
| Lead sponsor | Children's Hospital Medical Center, Cincinnati |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 16 |
| Start date | 20 March 2017 |
| Primary completion | 19 June 2018 |
| Estimated completion | 19 June 2018 |
| Sites | 1 location across United States |
Conditions studied
- Sickle Cell Anemia — all drugs for Sickle Cell Anemia →
Sponsor
Children's Hospital Medical Center, Cincinnati
Who can join
Adults 18 to 99, female only, with Sickle Cell Anemia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To examine the pharmacokinetics and distribution of oral hydroxyurea when administered as a single dose to lactating women
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease.
Ballas SK. · · 2020 · cited 36× · PMID 31934320 · DOI 10.4084/mjhid.2020.010
Verify or expand the search:
- PubMed search for NCT02990598
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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Other Children's Hospital Medical Center, Cincinnati trials
Trials by the same sponsor.
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- NCT07217444 — Improving Outcomes in Adolescent Inpatient Depression With Deep Transcranial Magnetic Stimulation · NA · recruiting
- NCT07195123 — Evaluation of the SMART IBD App in Pediatric IBD · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02990598 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Children's Hospital Medical Center, Cincinnati
- Last refreshed: 26 August 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02990598.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing