NCT02989467 is a Phase 1 clinical trial of Aprepitant in Healthy, sponsored by Mayo Clinic.

Who is sponsoring NCT02989467?

NCT02989467 is sponsored by Mayo Clinic.

What drugs are being tested in NCT02989467?

Interventions in NCT02989467: Aprepitant, Placebo.

Is NCT02989467 still recruiting?

NCT02989467 is currently completed. Last updated 12 December 2018.

Last reviewed 2018-12-12 · How we verify

NCT02989467

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Aprepitant on Satiation, Gastric Volume, Gastric Accommodation and Gastric Emptying

Completed Phase 1 Last updated 12 December 2018

What this trial tests

Phase 1 trial testing Aprepitant in Healthy in 27 participants. Completed in 1 January 2018.

Timeline

27 January 2017

Primary endpoint
20 November 2017

1 January 2018

Quick facts

Lead sponsor	Mayo Clinic
Phase	Phase 1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	27
Start date	27 January 2017
Primary completion	20 November 2017
Estimated completion	1 January 2018
Sites	1 location across United States

Drugs / interventions tested

Aprepitant (APREPITANT) — full drug profile →
Placebo

Conditions studied

Healthy — all drugs for Healthy →

Sponsor

Mayo Clinic

Who can join

Adults 18 to 65, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This research study is being done to compare the effects of Aprepitant and placebo on fasting gastric volume, accommodation volume, satiation (fullness) and gastric emptying.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Aprepitant

Trials testing the same drug.

NCT07371728 — Effect of Aprepitant on Post-operative Nausea and Vomiting in Otologic Surgery · Phase 4 · not yet recruiting
NCT04606264 — Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data · Phase 3 · completed
NCT05772676 — The Effect of Aprepitant Reducing Postoperative Nausea and Vomiting · Phase 4 · unknown
NCT05632224 — Postoperative Nausea and Vomiting in Laparoscopic Abdominal Surgery · Phase 4 · unknown
NCT04912271 — Granisetron Transdermal Patch for Prophylaxis of Delayed CINV · Phase 3 · unknown

Other recruiting trials for Healthy

Currently open trials in the same condition.

NCT06707207 — Predicting Future Errors During Skill Performance · recruiting
NCT07169630 — PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI) · Phase 1 · recruiting
NCT07499414 — The Effects of the Bile Acid Supplement, 7-keto Lithocholic Acid, on Human Gut Microbiota and Risk Factors for Disease. · NA · recruiting
NCT07496697 — Effects of Electroacupuncture at NP82 and SP15 on Bowel Motility in Healthy Subjects · NA · recruiting
NCT06431932 — Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity · Phase 1, PHASE2 · recruiting

Other Mayo Clinic trials

Trials by the same sponsor.

NCT07126548 — A Point of Prostate Cancer Diagnosis Virtual Reality Assistant Intervention in Supporting Newly Diagnosed Black Men · NA · not yet recruiting
NCT07221656 — Evaluation of Prolonged Asparaginase Activity Levels After Calaspargase Pegol Administration · not yet recruiting
NCT06891001 — The Utilization of a Shoe Insert on Individuals With Unilateral Greater Trochanteric Pain Syndrome on Single Leg Stance, · NA · not yet recruiting
NCT07169799 — Impact of Cryotherapy Spray (Tru-Freeze) for the Eradication of Gastric Antral Vascular Ectasia (ICE-GAVE) · NA · recruiting
NCT07086183 — Perioperative Risk in Patients on Chronic Aspirin Undergoing Craniotomy · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02989467 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Mayo Clinic
Last refreshed: 12 December 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02989467.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing