NCT02983773 is a Phase 2 clinical trial of THC 7.2% in Alcohol Drinking, sponsored by Brown University.

Who is sponsoring NCT02983773?

NCT02983773 is sponsored by Brown University.

What drugs are being tested in NCT02983773?

Interventions in NCT02983773: THC 7.2%, THC 3.0%, Placebo.

What condition does NCT02983773 study?

NCT02983773 studies Alcohol Drinking, Marijuana.

Is NCT02983773 still recruiting?

NCT02983773 is currently completed. Last updated 28 September 2021.

Last reviewed 2021-09-28 · How we verify

NCT02983773

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Marijuana's Impact on Alcohol Motivation and Consumption

Completed Phase 2 Last updated 28 September 2021

What this trial tests

Phase 2 trial testing THC 7.2% in Alcohol Drinking in 131 participants. Completed in 21 July 2021.

Timeline

23 January 2017

Primary endpoint
21 July 2021

21 July 2021

Quick facts

Lead sponsor	Brown University
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	basic science
Enrollment	131
Start date	23 January 2017
Primary completion	21 July 2021
Estimated completion	21 July 2021
Sites	1 location across United States

Drugs / interventions tested

THC 7.2% — full drug profile →
THC 3.0% — full drug profile →
Placebo

Conditions studied

Alcohol Drinking — all drugs for Alcohol Drinking →
Marijuana — all drugs for Marijuana →

Sponsor

Brown University

Who can join

Adults 21 to 44, any sex, with Alcohol Drinking or Marijuana. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This laboratory study will employ a repeated measures experimental design to examine the effect of high (7.2% THC) and moderate (3% THC) dose of marijuana, relative to placebo, on alcohol craving and on behavioral economic measure of alcohol demand after exposure to alcohol cues, and on subsequent drinking in an alcohol choice task in which participants choose either to drink or receive monetary reinforcement for drinks not consume. The study will recruit 173 non-treatment seeking heavy episodic alcohol drinkers who smoke marijuana at least twice weekly.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

The Use of Psychedelics in the Treatment of Medical Conditions: An Analysis of Currently Registered Psychedelics Studies in the American Drug Trial Registry.
Kurtz JS, Patel NA, Gendreau JL, Yang C, et al · · 2022 · cited 19× · PMID 36259015 · DOI 10.7759/cureus.29167
Acute Effects of Cannabis on Alcohol Craving and Consumption: A Randomized Controlled Crossover Trial.
Metrik J, Aston ER, Gunn RL, Swift R, et al · · 2026 · cited 4× · PMID 41254853 · DOI 10.1176/appi.ajp.20250115
Pharmacological interventions for alcohol use disorder: novel insights from recent clinical trials.
McManus KR, Ray LA. · · 2026 · PMID 41611606 · DOI 10.1080/17512433.2026.2625341

Verify or expand the search:

Other recruiting trials for Alcohol Drinking

Currently open trials in the same condition.

NCT07415707 — The GLUCID Study: Effect of Alcohol Reduction and Probiotic Interventions on Cognition and Brain Glucose Metabolism in N · NA · recruiting
NCT06815237 — Effects of Ketone Supplement and Alcohol on Brain Metabolism · Phase 2, PHASE3 · recruiting
NCT06994962 — Multi-Component Breath Alcohol Intervention Phase 3 · NA · recruiting
NCT05363878 — Development of a Culturally Grounded, Trauma-Informed Alcohol Intervention With a Reserve-Dwelling First Nation Group · NA · recruiting
NCT06309134 — The Healthy Families Bright Futures Program · NA · recruiting

Other Brown University trials

Trials by the same sponsor.

NCT07502872 — TPG: Tafasitamab, Polatuzumab Vedotin, and Glofitamab as First-line Therapy for Diffuse Large B-cell Lymphoma and High-g · Phase 2 · not yet recruiting
NCT07118618 — Probenecid Administration for Alcohol Craving and Consumption · Phase 2 · recruiting
NCT07398443 — Using Novel Behavioral Economic Measures to Characterize Dual Marijuana and Tobacco Use in Young Adults · NA · recruiting
NCT05901766 — Effect of Iodine-containing Multiple Micronutrient During Lactation on Infant Neurodevelopment · Phase 4 · not yet recruiting
NCT06974604 — Preventing Dato-DXd Associated Stomatitis With Dexamethasone Mouthwash, TROPION-DM · Phase 2 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02983773 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Brown University
Last refreshed: 28 September 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02983773.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing