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NCT02982928

Tylenol Levels in Bariatric Patients

Completed Results posted Last updated 19 June 2019
What this trial tests

trial in Obesity in 11 participants. Completed in 22 January 2018.

Timeline
6 March 2017
Primary endpoint
22 January 2018
22 January 2018

Quick facts

Lead sponsorNationwide Children's Hospital
StatusCompleted
Study typeOBSERVATIONAL
Enrollment11
Start date6 March 2017
Primary completion22 January 2018
Estimated completion22 January 2018
Sites1 location across United States

Conditions studied

Sponsor

Nationwide Children's Hospital

Who can join

Adults 12 to 21, any sex, with Obesity. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Intra- and Post-operative Serum Concentrations Primary · 15-20 minutes; 30-40 minutes; 50-70 minutes; 80-100 minutes; 2 Hours, 4 Hours; 8 Hours; and 12-Hours Post-IV acetaminophen administration

To determine whether adequate serum concentration of acetaminophen is achieved.

15-20 minutes
GroupValue95% CI
Bariatric Surgery17± 4
30-40 minutes
GroupValue95% CI
Bariatric Surgery14± 3
50-70 minutes
GroupValue95% CI
Bariatric Surgery9± 6
80-100 minutes
GroupValue95% CI
Bariatric Surgery5± 6
2 hours
GroupValue95% CI
Bariatric Surgery0± 0
4 hours
GroupValue95% CI
Bariatric Surgery0± 0
8 hours
GroupValue95% CI
Bariatric Surgery0± 0
12 hours
GroupValue95% CI
Bariatric Surgery0± 0

Sponsor's own description

The current study is designed to measure and evaluate the pharmacokinetic profiling of acetaminophen in the young obese patient population.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Practical Challenges-Use of Paracetamol in Children and Youth Who are Overweight or Obese: A Narrative Review.
    Zempsky WT, Bhagat PK, Siddiqui K. · · 2020 · cited 9× · PMID 32918268 · DOI 10.1007/s40272-020-00417-z

Verify or expand the search:

Other recruiting trials for Obesity

Currently open trials in the same condition.

Other Nationwide Children's Hospital trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02982928.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing