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Determination of the Antiplaque/Antigingivitis Efficacy of Essential Oil Containing Mouthrinses In a Six-Month Study
The objective of this randomized, single-center, examiner-blind, controlled, parallel group, six-month clinical study is to compare the antiplaque/antigingivitis potential of a no-alcohol essential oil containing mouthrinse and an alcohol essential oil containing mouthrinse. A negative control group using only an ADA Accepted anticavity toothpaste will be included.
Details
| Lead sponsor | Johnson & Johnson Consumer and Personal Products Worldwide |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 370 |
| Start date | 2013-09 |
| Completion | 2014-03 |
Conditions
- Plaque
- Gingivitis
- Gum Inflammation
- Bleeding
Interventions
- Listerine Zero Mouthwash (without alcohol)
- Listerine Antiseptic Mouthwash (with alcohol)
Primary outcomes
- Mean Modified Gingival Index (MGI) at 6 Months — 6 Months
Gingivitis was assessed on the buccal and lingual marginal gingivae and interdental papillae on all scoreable teeth on a 5-grade categorical scale of 0=normal to 4=severe inflammation.
Countries
Brazil