Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients. (AWAKE-HF)

NCT02970669 PHASE4 COMPLETED Results posted

The purpose of this study was to investigate the effects of initiation of sacubitril/valsartan vs enalapril treatment on objective measures of both waking activity and sleep in subjects with heart failure with reduced ejection fraction.

Details

Lead sponsor	Novartis Pharmaceuticals
Phase	PHASE4
Status	COMPLETED
Enrolment	140
Start date	Fri Dec 16 2016 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Mon Mar 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Heart Failure, Reduced Ejection Fraction

Interventions

• sacubitril/valsartan (LCZ696)
• enalapril
• matching placebo sacubitril/valsartan (LCZ696)
• matching placebo enalapril

Countries

United States