Erythrocyte Transfusion Based on the Measurement of Central Venous Oxygen Saturation in Postoperative Cardiac Surgery: a Bicentric, Prospective Randomized Study (PITT)

NCT02963883 NA COMPLETED

Postoperative erythrocytes transfusion is associated with morbidity and excess mortality, which should lead to ask the indication for RBC transfusions only on metabolic needs. Currently, the majority of studies used to put hemoglobin values indicating red cell transfusions. Two observational studies have confirmed that a transfusion strategy based on a metabolic index (ScvO2) individual was accompanied by a different transfusion strategy than using the hemoglobin threshold values. We propose to conduct the first randomized multicenter study to evaluate erythrocyte transfusion strategy in postoperative cardiac surgery using the ScvO2 each patient versus a threshold value usually recommended for all patients.

Details

Lead sponsor	Centre Hospitalier Universitaire, Amiens
Phase	NA
Status	COMPLETED
Enrolment	160
Start date	2016-12
Completion	2020-05-28

Conditions

• Cardiac Surgery

Interventions

• SVO2 group / control group

Primary outcomes

• Number of patients transfused — 15 dys
  Number of patients transfused at least one red blood cell concentrate in postoperative cardiac surgery for the ScvO2 group compared to the control group

Countries

France